An orally applicable Shiga toxin neutralizer functions in the intestine to inhibit the intracellular transport of the toxin. (Q42947533)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858299%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

An orally applicable Shiga toxin neutralizer functions in the intestine to inhibit the intracellular transport of the toxin (English)

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11 February 2020

7

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11 February 2020

author name string

Miho Watanabe-Takahashi

1

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11 February 2020

Toshio Sato

2

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11 February 2020

Taeko Dohi

3

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11 February 2020

Noriko Noguchi

4

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11 February 2020

Fumi Kano

5

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11 February 2020

Masayuki Murata

6

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11 February 2020

Yasuhiro Natori

8

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11 February 2020

Kiyotaka Nishikawa

9

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11 February 2020

language of work or name

English

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publication date

26 October 2009

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11 February 2020

published in

Infection and Immunity

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11 February 2020

volume

78

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11 February 2020

issue

1

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11 February 2020

page(s)

177-183

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A multivalent peptide library approach identifies a novel Shiga toxin inhibitor that induces aberrant cellular transport of the toxin

11 February 2020

cites work

1 reference

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Structural analysis of the interaction between Shiga toxin B subunits and linear polymers bearing clustered globotriose residues.

27 May 2018

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Interaction of Shiga toxin from Escherichia coli with human intestinal epithelial cell lines and explants: Stx2 induces epithelial damage in organ culture

27 May 2018

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Oral therapeutic agents with highly clustered globotriose for treatment of Shiga toxigenic Escherichia coli infections.

27 May 2018

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Assessment in mice of the therapeutic potential of tailored, multivalent Shiga toxin carbohydrate ligands

27 May 2018

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Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome

27 May 2018

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A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7.

27 May 2018

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Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives

27 May 2018

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Escherichia coli O157:H7 strains that express Shiga toxin (Stx) 2 alone are more neurotropic for gnotobiotic piglets than are isotypes producing only Stx1 or both Stx1 and Stx2.

27 May 2018

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Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands

27 May 2018

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Shiga toxins 1 and 2 translocate differently across polarized intestinal epithelial cells

27 May 2018

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Synthesis of an artificial glycoconjugate polymer carrying Pk-antigenic trisaccharide and its potent neutralization activity against Shiga-like toxin

27 May 2018

1 reference

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Intracellular targeting of the endoplasmic reticulum/nuclear envelope by retrograde transport may determine cell hypersensitivity to verotoxin via globotriaosyl ceramide fatty acid isoform traffic

27 May 2018

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Induction of cytokines in a human colon epithelial cell line by Shiga toxin 1 (Stx1) and Stx2 but not by non-toxic mutant Stx1 which lacks N-glycosidase activity

27 May 2018

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Pathogenesis and diagnosis of Shiga toxin-producing Escherichia coli infections

27 May 2018

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Enhancement of Susceptibility to Shiga Toxin-Producing Escherichia coli O157:H7 by Protein Calorie Malnutrition in Mice

27 May 2018

1 reference

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Structure of the Shiga-like Toxin I B-Pentamer Complexed with an Analogue of Its Receptor Gb3,

27 May 2018

1 reference

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Translocation of Shiga toxin across polarized intestinal cells in tissue culture

27 May 2018

1 reference

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Comparison of the relative toxicities of Shiga-like toxins type I and type II for mice

27 May 2018

1 reference

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Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP.

27 May 2018

1 reference

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Hemorrhagic Colitis Associated with a RareEscherichia coliSerotype

27 May 2018

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Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools

27 May 2018

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Acute undifferentiated human diarrhea in the tropics. I. Alterations in intestinal micrflora

27 May 2018

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The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli

27 May 2018

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27 May 2018

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Toxin genotypes and plasmid profiles as determinants of systemic sequelae in Escherichia coli O157:H7 infections

27 May 2018

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Investigation of Shiga-like Toxin Binding to Chemically Synthesized Oligosaccharide Sequences

27 May 2018

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Some properties of purified Escherichia coli heat-stable enterotoxin II

27 May 2018

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Purification and some properties of Shiga-like toxin from Escherichia coli O157:H7 that is immunologically identical to Shiga toxin.

27 May 2018

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The Shiga toxin 2 B subunit inhibits net fluid absorption in human colon and elicits fluid accumulation in rat colon loops.

27 May 2018

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Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7.

16 August 2018

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Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose.

16 August 2018

1 reference

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Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19858299

12 December 2020

inferred from PubMed ID database lookup

Calcium and protein kinase C play a significant role in response to Shigella toxin in rabbit ileum both in vivo and in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19858299

12 December 2020

inferred from PubMed ID database lookup

A new biological agent for treatment of Shiga toxigenic Escherichia coli infections and dysentery in humans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19858299

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/IAI.01022-09

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858299%20AND%20SRC:MED&resulttype=core&format=json

release_s7skwsahovecbcwb4caixjwwnq

11 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/s7skwsahovecbcwb4caixjwwnq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858299%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

19858299

1 reference