Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. (Q42944792)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615906%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination (English)

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1 November 2019

6

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1 November 2019

Takehiko Sasaki

7

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1 November 2019

5

Takeshi Tsubata

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1 November 2019

author name string

Akira Suzuki

1

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1 November 2019

Tsuneyasu Kaisho

2

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1 November 2019

Minako Ohishi

3

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1 November 2019

Manae Tsukio-Yamaguchi

4

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1 November 2019

Tak Wah Mak

8

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1 November 2019

Toru Nakano

9

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1 November 2019

language of work or name

English

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publication date

1 March 2003

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Journal of Experimental Medicine

1 November 2019

published in

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1 November 2019

volume

197

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1 November 2019

issue

5

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1 November 2019

page(s)

657-667

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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

1 November 2019

cites work

1 reference

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Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

27 May 2018

1 reference

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Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow

27 May 2018

1 reference

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Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice

27 May 2018

1 reference

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Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

27 May 2018

1 reference

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T-Independent immune response: new aspects of B cell biology

27 May 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

27 May 2018

1 reference

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Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

27 May 2018

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

27 May 2018

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Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

27 May 2018

1 reference

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SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

27 May 2018

1 reference

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

27 May 2018

1 reference

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

27 May 2018

1 reference

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Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

27 May 2018

1 reference

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

27 May 2018

1 reference

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PTEN: Sometimes Taking It Off Can Be Better than Putting It On

27 May 2018

1 reference

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Germline mutations in PTEN are present in Bannayan-Zonana syndrome

27 May 2018

1 reference

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Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

27 May 2018

1 reference

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B lymphocyte-specific, Cre-mediated mutagenesis in mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

27 May 2018

1 reference

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Expression of I mu-C gamma hybrid germline transcripts subsequent to immunoglobulin heavy chain class switching

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

Anti-nuclear antibody production and immune-complex glomerulonephritis in BALB/c mice treated with pristane

27 May 2018

1 reference

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Immunoglobulin class switching: molecular and cellular analysis

27 May 2018

1 reference

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Cells in the marginal zone of the spleen

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

Quantitation of immunoglobulin mu-gamma 1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

Characteristics and development of the murine B-1b (Ly-1 B sister) cell population

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens

16 August 2018

1 reference

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Loss of PTEN expression leading to high Akt activation in human multiple myelomas

16 August 2018

1 reference

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Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

16 August 2018

1 reference

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The origin of marginal zone B cells in the rat.

16 August 2018

1 reference

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IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells.

16 August 2018

1 reference

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Mutational analysis of the PTEN/MMAC1 gene in non-Hodgkin's lymphoma

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20021101

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193827

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

3 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20021101

Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20021101

Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity

21 January 2018

1 reference

12 December 2020

Mice deficient for the CD40 ligand

1 reference

12 December 2020

Alterations of the MMAC1/PTEN gene in lymphoid malignancies

1 reference

12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

12 December 2020

B cells on the front line

1 reference

12 December 2020

Marginal zones: the major B cell compartment of rat spleens

1 reference

12 December 2020

Further evidence for coelomic-associated B lymphocytes

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20021101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615906%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615906%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

12615906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615906%20AND%20SRC:MED&resulttype=core&format=json