UCS15A, a non-kinase inhibitor of Src signal transduction (Q42828816)

8 November 2017

title

UCS15A, a non-kinase inhibitor of Src signal transduction (English)

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8 November 2017

S V Sharma

1

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8 November 2017

C Oneyama

2

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8 November 2017

Y Yamashita

3

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8 November 2017

H Nakano

4

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8 November 2017

K Sugawara

5

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8 November 2017

M Hamada

6

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8 November 2017

N Kosaka

7

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8 November 2017

T Tamaoki

8

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8 November 2017

language of work or name

English

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publication date

1 April 2001

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8 November 2017

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8 November 2017

volume

20

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8 November 2017

issue

17

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8 November 2017

page(s)

2068-2079

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Preparation and characterization of a mouse osteoclast-like multinucleated cell population.

8 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Activation of pp60c-src protein kinase activity in human colon carcinoma

21 January 2018

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Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

21 January 2018

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Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling

21 January 2018

1 reference

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Expression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cells

21 January 2018

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Altered phosphorylation and activation of pp60c-src during fibroblast mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

While E1A can facilitate epithelial cell transformation by several dominant oncogenes, the C-terminus seems only to regulate rac and cdc42 function, but in both epithelial and fibroblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Deletions in the SH2 domain of p60v-src prevent association with the detergent-insoluble cellular matrix

21 January 2018

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A target for Src in mitosis.

21 January 2018

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Role of carbonic anhydrase in bone resorption: effect of acetazolamide on basal and parathyroid hormone-induced bone metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

1 reference

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c-Src association with and phosphorylation of p58gag, a membrane- and microfilament-associated retroviral Gag-like protein in a xenotransplantable rat mammary tumor

21 January 2018

1 reference

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Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

21 January 2018

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Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

21 January 2018

1 reference

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c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Characterization of avian and viral p60src proteins expressed in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Morphology of ras-transformed cells becomes apparently normal again with tyrosine kinase inhibitors without a decrease in the ras-GTP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

In vitro and in vivo suppression of osteoclast function by adenovirus vector-induced csk gene.

21 January 2018

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Cell biology of the osteoclast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Rescue of osteoclast function by transgenic expression of kinase-deficient Src insrc−/− mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Targeting of the protein chaperone, HSP90, by the transformation suppressing agent, radicicol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Use of an oriented peptide library to determine the optimal substrates of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Cellular functions regulated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

A Src SH2 selective binding compound inhibits osteoclast-mediated resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Identification and characterization of a novel cytoskeleton-associated pp60src substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Regulation, substrates and functions of src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Evidence that c-src is involved in the process of osteoclastic bone resorption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Radicicol, an agent inducing the reversal of transformed phenotypes of src-transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

The many faces of Src: multiple functions of a prototypical tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

A useful method to evaluate bone resorption inhibitors, using osteoclast-like multinucleated cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Effects of herbimycin derivatives on src oncogene function in relation to antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204296

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204296

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Dimensions Publication ID

8 November 2017

1037123077

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1 reference