TYK2 activity promotes ligand-induced IFNAR1 proteolysis (Q42407864)

29 October 2017

TYK2 activity promotes ligand-induced IFNAR1 proteolysis (English)

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29 October 2017

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Sandra Pellegrini

5

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author name string

Zrinka Marijanovic

1

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29 October 2017

Josiane Ragimbeau

2

1 reference

29 October 2017

K G Suresh Kumar

3

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29 October 2017

Serge Y Fuchs

4

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29 October 2017

language of work or name

English

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publication date

1 July 2006

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29 October 2017

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29 October 2017

397

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29 October 2017

1

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29 October 2017

31-38

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Janus kinases affect thrombopoietin receptor cell surface localization and stability

29 October 2017

1 reference

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Clathrin-independent endocytosis of ubiquitinated cargos

28 May 2018

1 reference

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Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

28 May 2018

1 reference

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Interferons, interferon-like cytokines, and their receptors

28 May 2018

1 reference

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Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Regulated proteolysis of the IFNaR2 subunit of the interferon-alpha receptor

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase

28 May 2018

1 reference

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Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

28 May 2018

1 reference

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Receptor endocytosis via ubiquitin-dependent and -independent pathways

28 May 2018

1 reference

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SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon- receptor

28 May 2018

1 reference

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Molecular phylogeny within type I cytokines and their cognate receptors

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1 reference

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Endosomal dynamics of Met determine signaling output

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

28 May 2018

1 reference

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Receptor downregulation and multivesicular-body sorting

28 May 2018

1 reference

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Signaling through the JAK/STAT pathway, recent advances and future challenges

28 May 2018

1 reference

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The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor

28 May 2018

1 reference

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Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway

28 May 2018

1 reference

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Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

28 May 2018

1 reference

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Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor beta chain to late endocytic compartments

28 May 2018

1 reference

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Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes

28 May 2018

1 reference

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The type I interferon receptor: structure, function, and evolution of a family business.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

The Janus kinase family of protein tyrosine kinases and their role in signaling

28 May 2018

1 reference

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Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

28 May 2018

1 reference

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Linkage of the ubiquitin-conjugating system and the endocytic pathway in ligand-induced internalization of the growth hormone receptor

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479745

Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chains

28 May 2018

1 reference

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Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase

28 May 2018

1 reference

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Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

28 May 2018

1 reference

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Ligand-induced assembling of the type I interferon receptor on supported lipid bilayers

28 May 2018

1 reference

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Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression.

16 August 2018

1 reference

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The receptor interaction region of Tyk2 contains a motif required for its nuclear localization.

16 August 2018

1 reference

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Characterization of Antihuman IFNAR-1 Monoclonal Antibodies: Epitope Localization and Functional Analysis

16 August 2018

1 reference

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Activation of the erythropoietin receptor is not required for internalization of bound erythropoietin

1 December 2018

1 reference

12 December 2020

The two subunits of the interleukin-4 receptor mediate independent and distinct patterns of ligand endocytosis

1 reference

12 December 2020

Both proteasomes and lysosomes degrade the activated erythropoietin receptor

1 reference

12 December 2020

Endocytosis and degradation of the growth hormone receptor are proteasome-dependent

1 reference

12 December 2020

Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited

1 reference

12 December 2020

Human type I interferon receptor, IFNAR, is a heavily glycosylated 120-130 kD membrane protein

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20060272

1 reference

29 October 2017

1 reference

29 October 2017

PubMed publication ID

16551269

1 reference