Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia. (Q42369829)

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scientific article published on 29 September 2017

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English	Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia.	scientific article published on 29 September 2017

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7 April 2020

Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia (English)

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7 April 2020

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7 April 2020

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Valentina Tosato

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7 April 2020

Nicole West

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7 April 2020

Dmitri V Nikitin

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7 April 2020

Giannino Del Sal

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7 April 2020

Roberto Marano

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7 April 2020

Michael Breitenbach

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7 April 2020

Carlo V Bruschi

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29 September 2017

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7 April 2020

Frontiers in Oncology

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7 April 2020

231

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7 April 2020

TP53-induced glycolysis and apoptosis regulator protects from spontaneous apoptosis and predicts poor prognosis in chronic lymphocytic leukemia

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Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype

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Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint

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Fast Prediction of DNA Melting Bubbles Using DNA Thermodynamic Stability.

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Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

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Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia.

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p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q).

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Control of Cdc28 CDK1 by a stress-induced lncRNA

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29 May 2018

Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway

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Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes

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Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model

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NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

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p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.

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p53 Protects lung cancer cells against metabolic stress

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29 May 2018

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29 May 2018

Supercoil-driven DNA structures regulate genetic transactions

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NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells

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NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.

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29 May 2018

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29 May 2018

GC-rich DNA sequences block homologous recombination in vitro.

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17 August 2018

p53 Maintains Genomic Stability by Preventing Interference between Transcription and Replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

High reactive oxygen species levels are detected at the end of the chronological life span of translocant yeast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Overexpression of MLN51 triggers P-body disassembly and formation of a new type of RNA granules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Chromosome translocation may lead to PRK1-dependent anticancer drug resistance in yeast via endocytic actin network deregulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Novel simplified yeast-based assays of regulators of p53-MDMX interaction and p53 transcriptional activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Human p53 induces cell death and downregulates thioredoxin expression in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

DNA bridging of yeast chromosomes VIII leads to near-reciprocal translocation and loss of heterozygosity with minor cellular defects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

PCR-mediated seamless gene deletion and marker recycling in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Abnormalities of the P53, MDM2, BCL2 and BAX genes in acute leukemias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Non-reciprocal chromosomal bridge-induced translocation (BIT) by targeted DNA integration in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Coexpression of p53 protein and MDR functional phenotype in leukemias: the predominant association in chronic myeloid leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Determination of common structural features in Escherichia coli promoters by computer analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Suppression of the Yeast Mutation rft1-1 by Human p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5626878

17 August 2018

Endocytosis in yeast: Several of the yeast secretory mutants are defective in endocytosis

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2017.00231

21 January 2018

Modulation of DNA Topoisomerase I Activity byp53

1 reference

https://api.crossref.org/works/10.3389%2FFONC.2017.00231

21 January 2018

Origin of Auer bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of DNA Bending in Flp-mediated Site-specific Recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Position effect in human genetic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of p53 function by protein kinase C isoforms revealed by a yeast cell system

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the p53 gene in acute myeloid leukemia patients correlate with poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High frequency FLP-independent homologous DNA recombination of 2 mu plasmid in the yeast Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53 protein expression in human leukemia and lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of cytarabine and topotecan in patients treated for acute myeloid leukemia with persistent disease after frontline induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29034209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FONC.2017.00231

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29034209%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29034209%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29034209%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

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