Determinants of the assembly and function of antibody variable domains (Q42143637)

17 October 2017

Determinants of the assembly and function of antibody variable domains (English)

1 reference

17 October 2017

8

Martin Zacharias

1 reference

17 October 2017

Eva Maria Herold

1

1 reference

17 October 2017

Christine John

2

1 reference

17 October 2017

Benedikt Weber

3

1 reference

17 October 2017

Stephan Kremser

4

1 reference

17 October 2017

Jonathan Eras

5

1 reference

17 October 2017

Carolin Berner

6

1 reference

17 October 2017

Sabrina Deubler

7

1 reference

17 October 2017

Johannes Buchner

9

1 reference

17 October 2017

language of work or name

English

0 references

publication date

25 September 2017

1 reference

17 October 2017

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17 October 2017

7

1 reference

17 October 2017

1

1 reference

17 October 2017

12276

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Creative Commons Attribution 4.0 International

17 October 2017

start time

25 September 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation

29 May 2018

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A residue-specific shift in stability and amyloidogenicity of antibody variable domains

29 May 2018

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29 May 2018

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29 May 2018

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An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.

29 May 2018

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Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework

29 May 2018

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Critical contribution of VH-VL interaction to reshaping of an antibody: The case of humanization of anti-lysozyme antibody, HyHEL-10

29 May 2018

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29 May 2018

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Folding mechanism of the CH2 antibody domain.

29 May 2018

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Stability improvement of antibodies for extracellular and intracellular applications: CDR grafting to stable frameworks and structure-based framework engineering

29 May 2018

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Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor

29 May 2018

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An improved model of association for VH-VL immunoglobulin domains: asymmetries between VH and VL in the packing of some interface residues.

29 May 2018

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Biophysical properties of human antibody variable domains

29 May 2018

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Submolecular cooperativity produces multi-state protein unfolding and refolding

29 May 2018

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29 May 2018

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Functional mapping of conserved, surface-exposed charges of antibody variable domains.

29 May 2018

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The importance of framework residues H6, H7 and H10 in antibody heavy chains: experimental evidence for a new structural subclassification of antibody V(H) domains

29 May 2018

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Stability engineering of antibody single-chain Fv fragments

29 May 2018

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Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity

29 May 2018

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Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

29 May 2018

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Contributions of a highly conserved VH/VL hydrogen bonding interaction to scFv folding stability and refolding efficiency

29 May 2018

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Construction and characterisation of a functional CD19 specific single chain Fv fragment for immunotherapy of B lineage leukaemia and lymphoma

29 May 2018

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29 May 2018

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The immunoglobulin fold. Structural classification, sequence patterns and common core

29 May 2018

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Domain association in immunoglobulin molecules. The packing of variable domains

29 May 2018

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Folding pathways of immunoglobulin domains. The folding kinetics of the C.gamma.3 domain of human IgG1

29 May 2018

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A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions.

29 May 2018

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Principles and engineering of antibody folding and assembly.

17 August 2018

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Mechanical stability of the antibody domain CH3 homodimer in different oxidation states

17 August 2018

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Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions

17 August 2018

1 reference

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Analysis and prediction of VH/VL packing in antibodies.

17 August 2018

1 reference

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The folding pathway of the antibody V(L) domain

17 August 2018

1 reference

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Energy-based analysis and prediction of the orientation between light- and heavy-chain antibody variable domains

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

The influence of the framework core residues on the biophysical properties of immunoglobulin heavy chain variable domains

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

Conserved amino acid networks involved in antibody variable domain interactions

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

Revealing the set of mutually correlated positions for the protein families of immunoglobulin fold

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

The influence of the buried glutamine or glutamate residue in position 6 on the structure of immunoglobulin variable domains

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

Effects on interaction kinetics of mutations at the VH-VL interface of Fabs depend on the structural context

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

Conformations of the third hypervariable region in the VH domain of immunoglobulins

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5613017

'Camelising' human antibody fragments: NMR studies on VH domains.

17 August 2018

1 reference

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GROMACS: A message-passing parallel molecular dynamics implementation

17 August 2018

1 reference

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Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-12519-9

Biophysical Properties of Camelid VHHDomains Compared to Those of Human VH3 Domains†

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-12519-9

Structural determinants in the sequences of immunoglobulin variable domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-12519-9

7 January 2021

inferred from DOI database lookup

Functional mapping of conserved residues located at the VL and VH domain interface of a Fab

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-12519-9

7 January 2021

inferred from DOI database lookup

Mapping IgG epitopes bound by rheumatoid factors from immunized controls identifies disease-specific rheumatoid factors produced by patients with rheumatoid arthritis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28947772

12 December 2020

inferred from PubMed ID database lookup

Unfolding free energy changes determined by the linear extrapolation method. 2. Incorporation of delta G degrees N-U values in a thermodynamic cycle.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28947772

12 December 2020

inferred from PubMed ID database lookup

The Immunoglobulin Fold

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28947772

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41598-017-12519-9

1 reference

17 October 2017

1 reference

17 October 2017

PubMed publication ID

28947772

1 reference