The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation (Q42143163)

17 October 2017

The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation (English)

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17 October 2017

5

Joann B Sweasy

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17 October 2017

Tieming Lang

1

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17 October 2017

Shibani Dalal

series ordinal

2

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17 October 2017

Anna Chikova

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3

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17 October 2017

Daniel DiMaio

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4

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17 October 2017

language of work or name

English

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publication date

25 May 2007

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Molecular and Cellular Biology

17 October 2017

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17 October 2017

27

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17 October 2017

15

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17 October 2017

5587-5596

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describes a project that uses

17 October 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1952088/fullTextXML

inferred from PubMed Central ID database lookup

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A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair

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Completion of base excision repair by mammalian DNA ligases

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Functional mutation of DNA polymerase beta found in human gastric cancer--inability of the base excision repair in vitro.

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29 May 2018

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

29 May 2018

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29 May 2018

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29 May 2018

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Errors in DNA replication as a basis of malignant changes

29 May 2018

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Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses.

29 May 2018

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12 December 2020

Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity

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12 December 2020

Two Pathways for Base Excision Repair in Mammalian Cells

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12 December 2020

Alternative splicing of DNA polymerase beta mRNA is not tumor-specific

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12 December 2020

Prostate-cancer-associated I260M variant of DNA polymerase beta is a sequence-specific mutator

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Identifiers

DOI

10.1128/MCB.01883-06

1 reference

17 October 2017

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17 October 2017

PubMed publication ID

17526740

1 reference