Power and pitfalls of using transgenic mice to optimize therapy for CPVT: A need for prospective placebo-controlled clinical trials in genetic arrhythmia disorders (Q41988117)

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scientific article published on July 29, 2010

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English	Power and pitfalls of using transgenic mice to optimize therapy for CPVT: A need for prospective placebo-controlled clinical trials in genetic arrhythmia disorders	scientific article published on July 29, 2010

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9 February 2020

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Power and pitfalls of using transgenic mice to optimize therapy for CPVT: a need for prospective placebo-controlled clinical trials in genetic arrhythmia disorders (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20673814%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Power and pitfalls of using transgenic mice to optimize therapy for CPVT: A need for prospective placebo-controlled clinical trials in genetic arrhythmia disorders (English)

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10.1016/J.HRTHM.2010.07.028

https://api.crossref.org/works/10.1016/J.HRTHM.2010.07.028

14 June 2024

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Bjorn C. Knollmann

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9 February 2020

Bjorn C. Knollmann

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Björn C Knollmann

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14 October 2017

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29 July 2010

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9 February 2020

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14 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20673814/?tool=EBI

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14 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20673814/pdf/?tool=EBI

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14 June 2024

https://europepmc.org/articles/PMC2970718

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Europe PubMed Central

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14 June 2024

https://europepmc.org/articles/PMC2970718?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20673814

14 June 2024

https://doi.org/10.1016/j.hrthm.2010.07.028

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14 June 2024

https://api.elsevier.com/content/article/PII:S1547527110007381?httpAccept=text/xml

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10.1016/J.HRTHM.2010.07.028

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14 June 2024

https://api.elsevier.com/content/article/PII:S1547527110007381?httpAccept=text/plain

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10.1016/J.HRTHM.2010.07.028

https://api.crossref.org/works/10.1016/J.HRTHM.2010.07.028

14 June 2024

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9 February 2020

7

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9 February 2020

11

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9 February 2020

1683-1685

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9 February 2020

Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

A genetic framework for improving arrhythmia therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Catecholaminergic polymorphic ventricular tachycardia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

5 June 2018

Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

18 August 2018

Effects of changes in left ventricular contractility on indexes of contractility in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970718

18 August 2018

Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20673814

12 December 2020

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10.1016/J.HRTHM.2010.07.028

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20673814%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20673814%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20673814%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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