Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation. (Q41896659)

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17 January 2020

title

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation (English)

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17 January 2020

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Aloysius J. Klingelhutz

3

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17 January 2020

Eiyu Matsumoto

7

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17 January 2020

Douglas R Spitz

9

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17 January 2020

11

Gary W Hunninghake

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17 January 2020

author name string

Toru Nyunoya

1

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17 January 2020

Martha M Monick

2

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17 January 2020

Heather Glaser

4

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17 January 2020

Jeffrey R Cagley

5

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17 January 2020

Charles O Brown

6

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17 January 2020

Nukhet Aykin-Burns

8

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17 January 2020

Junko Oshima

10

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17 January 2020

language of work or name

English

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publication date

14 November 2008

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American Journal of Respiratory and Critical Care Medicine

17 January 2020

published in

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17 January 2020

volume

179

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17 January 2020

issue

4

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17 January 2020

page(s)

279-287

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A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury

17 January 2020

cites work

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Cigarette smoke induces cellular senescence

5 June 2018

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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Lung fibroblasts from patients with emphysema show markers of senescence in vitro

5 June 2018

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5 June 2018

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Cigarette smoke extract inhibits expression of peroxiredoxin V and increases airway epithelial permeability

5 June 2018

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Werner protein protects nonproliferating cells from oxidative DNA damage

5 June 2018

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Deficient DNA repair in the human progeroid disorder, Werner syndrome

5 June 2018

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5 June 2018

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SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling

5 June 2018

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Effects of "second-hand" smoke on structure and function of fibroblasts, cells that are critical for tissue repair and remodeling

5 June 2018

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5 June 2018

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Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts

5 June 2018

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Unwinding the molecular basis of the Werner syndrome

5 June 2018

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What geriatricians should know about the Werner syndrome

5 June 2018

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Effect of cigar smoking on the risk of cardiovascular disease, chronic obstructive pulmonary disease, and cancer in men.

5 June 2018

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5 June 2018

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Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.

5 June 2018

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Replication focus-forming activity 1 and the Werner syndrome gene product

5 June 2018

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5 June 2018

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Positional cloning of the Werner's syndrome gene

5 June 2018

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Family analysis of Werner's syndrome: a survey of 42 Japanese families with a review of the literature

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Role for the Werner syndrome protein in the promotion of tumor cell growth.

5 June 2018

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Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema.

18 August 2018

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Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation

18 August 2018

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Firsthand cigarette smoke alters fibroblast migration and survival: implications for impaired healing

18 August 2018

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Reversible cigarette smoke extract-induced DNA damage in human lung fibroblasts.

18 August 2018

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Hyperoxia induces macrophage cell cycle arrest by adhesion-dependent induction of p21Cip1 and activation of the retinoblastoma protein.

18 August 2018

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18 August 2018

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Accelerated methylation of ribosomal RNA genes during the cellular senescence of Werner syndrome fibroblasts

18 August 2018

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18 August 2018

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Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy

2 December 2018

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12 December 2020

Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture

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12 December 2020

Effects of cigarette smoking on rate of loss of pulmonary function in adults: a longitudinal assessment

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12 December 2020

Cigarette smoke inhibits lung fibroblast proliferation and chemotaxis

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12 December 2020

DNA helicases: the long unwinding road

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12 December 2020

Alveolar cell senescence in patients with pulmonary emphysema

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12 December 2020

Metal-catalyzed oxidation of the Werner syndrome protein causes loss of catalytic activities and impaired protein-protein interactions

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12 December 2020

Cigar smoking and death from coronary heart disease in a prospective study of US men

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Lack of WRN results in extensive deletion at nonhomologous joining ends

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10.1164/RCCM.200802-320OC

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19011155%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19011155%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19011155

1 reference