The β-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22. (Q41812432)

12 October 2017

The β-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22. (English)

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12 October 2017

6

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12 October 2017

Lauren M Lilly

1

1 reference

12 October 2017

Melissa A Gessner

2

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12 October 2017

Chad W Dunaway

3

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12 October 2017

Allison E Metz

4

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12 October 2017

Lisa Schwiebert

5

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12 October 2017

Gordon D Brown

7

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12 October 2017

Chad Steele

8

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12 October 2017

language of work or name

English

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publication date

29 August 2012

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12 October 2017

Journal of Immunology

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12 October 2017

189

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12 October 2017

7

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12 October 2017

3653-3660

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IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Interleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A.

6 June 2018

1 reference

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IL-35 production by inducible costimulator (ICOS)–positive regulatory T cells reverses established IL-17–dependent allergic airways disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infection.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Targeting ST2L potentiates CpG-mediated therapeutic effects in a chronic fungal asthma model

6 June 2018

1 reference

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Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice

6 June 2018

1 reference

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TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

6 June 2018

1 reference

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Interleukin-33: a novel mediator with a role in distinct disease pathologies.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

6 June 2018

1 reference

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Mucosal sensitization to German cockroach involves protease-activated receptor-2.

6 June 2018

1 reference

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Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

6 June 2018

1 reference

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The molecular phenotype of severe asthma in children.

6 June 2018

1 reference

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Importance of cytokines in murine allergic airway disease and human asthma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma: systematic review and meta-analysis.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IL-33 exacerbates antigen-induced arthritis by activating mast cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Usefulness and optimization of mouse models of allergic airway disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

6 June 2018

1 reference

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IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

6 June 2018

1 reference

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Dectin-1 is required for beta-glucan recognition and control of fungal infection

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

Interleukin-17 is a negative regulator of established allergic asthma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

The link between fungi and severe asthma: a summary of the evidence.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

IL-22 increases the innate immunity of tissues

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

High frequency of atopic asthma in a pulmonary clinic population.

6 June 2018

1 reference

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IL-33 induces Th17-mediated airway inflammation via mast cells in ovalbumin-challenged mice.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448838

T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma

18 August 2018

1 reference

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Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study

18 August 2018

1 reference

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Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

18 August 2018

1 reference

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Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic fibrosis

18 August 2018

1 reference

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Neutrophils regulate airway responses in a model of fungal allergic airways disease.

18 August 2018

1 reference

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Sensitization to Aspergillus antigens and occurrence of allergic bronchopulmonary aspergillosis in patients with asthma

18 August 2018

1 reference

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Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5.

18 August 2018

1 reference

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Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma

18 August 2018

1 reference

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Dual Role of IL-22 in Allergic Airway Inflammation and its Cross-talk with IL-17A

18 August 2018

1 reference

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Neutrophilic inflammation in severe persistent asthma

2 December 2018

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Bronchial Neutrophilia in Patients with Noninfectious Status Asthmaticus

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12 December 2020

Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis

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Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis

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IL-22 mRNA in peripheral blood mononuclear cells from allergic rhinitic and asthmatic pediatric patients

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1201797

1 reference

12 October 2017

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12 October 2017

PubMed publication ID

22933634

1 reference