A co-clinical platform to accelerate cancer treatment optimization. (Q41736028)

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24 February 2020

title

A co-clinical platform to accelerate cancer treatment optimization (English)

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24 February 2020

1

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24 February 2020

Pier Paolo Pandolfi

series ordinal

2

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24 February 2020

publication date

17 November 2014

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Trends in Molecular Medicine

24 February 2020

published in

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24 February 2020

volume

21

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24 February 2020

issue

1

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24 February 2020

page(s)

1-5

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

24 February 2020

cites work

1 reference

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Intratumour heterogeneity in urologic cancers: from molecular evidence to clinical implications

30 June 2018

1 reference

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Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

30 June 2018

1 reference

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

30 June 2018

1 reference

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Co-clinical trials demonstrate superiority of crizotinib to chemotherapy in ALK-rearranged non-small cell lung cancer and predict strategies to overcome resistance

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Noncoding RNA in oncogenesis: a new era of identifying key players

30 June 2018

1 reference

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A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer

30 June 2018

1 reference

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Long noncoding RNAs and the genetics of cancer.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

30 June 2018

Cancer statistics, 2013

1 reference

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The mutational landscape of lethal castration-resistant prostate cancer

30 June 2018

1 reference

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A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

The APL paradigm and the "co-clinical trial" project

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Molecular genetics of prostate cancer: new prospects for old challenges

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Integrative genomic profiling of human prostate cancer

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

30 June 2018

1 reference

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30 June 2018

1 reference

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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Causes of death in men with prostate cancer: an analysis of 50,000 men from the Thames Cancer Registry

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Eradication of acute promyelocytic leukemia-initiating cells by PML/RARA-targeting

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005181

Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25466492

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosomal patterns in myelocytic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25466492

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Next-generation sequencing in precision oncology: challenges and opportunities

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25466492

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLMED.2014.10.008

1 reference

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24 February 2020

1 reference

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24 February 2020

PubMed publication ID

25466492

1 reference