Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival (Q41479119)

1 October 2017

Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival (English)

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1 October 2017

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2

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1 October 2017

Ian B Fisher

1

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1 October 2017

Natarajan Muthusamy

series ordinal

3

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1 October 2017

language of work or name

English

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publication date

29 November 2011

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Journal of Biological Chemistry

1 October 2017

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1 October 2017

287

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1 October 2017

8

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1 October 2017

5199-5210

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An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Ets-1 is a negative regulator of Th17 differentiation

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Ets-2 interacts with co-repressor BS69 to repress target gene expression

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

The role of the Ets2 transcription factor in the proliferation, maturation, and survival of mouse thymocytes

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Transgenic analysis of thymocyte signal transduction

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Fine tuning of TCR signaling by CD5.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Altered Ets transcription factor activity in prostate tumor cells inhibits anchorage-independent growth, survival, and invasiveness

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

The role of SLP-76 and LAT in lymphocyte development

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Control of interferon-tau gene expression by Ets-2

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Defective trophoblast function in mice with a targeted mutation of Ets2.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Two distinct pathways of positive selection for thymocytes

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Positive and negative selection invoke distinct signaling pathways.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Involvement of p21ras distinguishes positive and negative selection in thymocytes

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Essential role for ZAP-70 in both positive and negative selection of thymocytes

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Defective activation and survival of T cells lacking the Ets-1 transcription factor

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Phosphorylation of the ETS-2 protein: regulation by the T-cell antigen receptor-CD3 complex

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

MEK activity regulates negative selection of immature CD4+CD8+ thymocytes

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285301

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

19 August 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.242602

A role for CD5 in TCR-mediated signal transduction and thymocyte selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.242602

Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.242602

Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.242602

T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

21 January 2018

1 reference

12 December 2020

Raf regulates positive selection

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12 December 2020

The Ets-1 transcription factor is required for the development of natural killer cells in mice

1 reference

12 December 2020

Degree of ERK activation influences both positive and negative thymocyte selection

1 reference

12 December 2020

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

1 reference

12 December 2020

CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection

1 reference

12 December 2020

NF-kappa B is required for the positive selection of CD8+ thymocytes

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.242602

1 reference

1 October 2017

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1 October 2017

PubMed publication ID

22128184

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