Mitochondrial diseases and aging. (Q41378809)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

review article

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title

Mitochondrial diseases and aging (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1

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1 November 2019

Salvatore Scacco

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

4

J Trappe

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

M Schliebs

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

P Seibel

series ordinal

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

publication date

1 December 1996

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Molecular Aspects of Medicine

1 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

6

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1 November 2019

page(s)

513-563

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

1 November 2019

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Mitochondrial diabetes revisited

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Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

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Ageing is associated in females with a decline in the content and activity on the b-c1 complex in skeletal muscle mitochondria

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7 January 2021

A single base change in the extra-arm of yeast mitochondrial tyrosine tRNA affects its conformational stability and impairs aminoacylation

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7 January 2021

The cellular production of hydrogen peroxide

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7 January 2021

Oxidative phosphorylation and photophosphorylation

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Oxidative stress as a mediator of apoptosis

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Biochemistry of oxygen toxicity

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Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

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7 January 2021

Factors affecting the H+/e- stoichiometry in mitochondrial cytochrome c oxidase: influence of the rate of electron flow and transmembrane delta pH

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Decreased cytochrome-c oxidase activity and lack of age-related accumulation of mitochondrial DNA deletions in the brains of schizophrenics.

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7 January 2021

Hydroperoxide metabolism in mammalian organs

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7 January 2021

A mammalian mitochondrial RNA processing activity contains nucleus-encoded RNA.

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7 January 2021

Mouse RNAase MRP RNA is encoded by a nuclear gene and contains a decamer sequence complementary to a conserved region of mitochondrial RNA substrate.

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7 January 2021

The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation

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7 January 2021

Spermine Effect on the Binding of Casein Kinase I to the Rat Liver Mitochondrial Structures

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7 January 2021

Nuclear gadgets in mitochondrial DNA replication and transcription

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7 January 2021

Transcription and replication of animal mitochondrial DNAs.

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7 January 2021

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

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7 January 2021

The control of apoptosis in mammalian cells

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7 January 2021

ATP synthase from bovine heart mitochondria. In vitro assembly of a stalk complex in the presence of F1-ATPase and in its absence

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7 January 2021

Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing

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7 January 2021

Modelling the effects of age-related mtDNA mutation accumulation; Complex I deficiency, superoxide and cell death

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7 January 2021

A second missense mutation in the mitochondrial ATPase 6 gene in Leigh's syndrome

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7 January 2021

Mitochondrial myopathies

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7 January 2021

MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination

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7 January 2021

Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain

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7 January 2021

Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation

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7 January 2021

Superoxide radical and superoxide dismutases

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7 January 2021

Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of L-carnitine

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7 January 2021

Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats

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7 January 2021

Down-regulation of mitochondrial mRNAs in the mdx mouse model for Duchenne muscular dystrophy

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7 January 2021

Import of proteins into mitochondria

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7 January 2021

Protein sorting in mitochondria

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7 January 2021

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

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7 January 2021

Age-dependent changes in the mitochondrial F0F1 ATP synthase

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7 January 2021

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7 January 2021

Evidence for intramitochondrial complementation between deleted and normal mitochondrial DNA in some patients with mitochondrial myopathy

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7 January 2021

Bioenergetics in aging

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7 January 2021

Free Radical Theory of Aging: Effect of Free Radical Reaction Inhibitors on the Mortality Rate of Male LAF1 Mice

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7 January 2021

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

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7 January 2021

Control of mitochondrial ATP synthesis in the heart

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7 January 2021

Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion

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7 January 2021

The mitochondrial electron transport and oxidative phosphorylation system

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7 January 2021

Amino acid identities in the three redox center-carrying polypeptides of cytochrome bc1/b6f complexes

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7 January 2021

Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm

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7 January 2021

Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells

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7 January 2021

Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies

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7 January 2021

Cardiolipins and biomembrane function

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7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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7 January 2021

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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7 January 2021

Electron microscopic analysis of the peripheral and membrane parts of mitochondrial NADH dehydrogenase (Complex I)

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7 January 2021

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

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7 January 2021

Rapid stimulation of hepatic oxygen consumption by 3,5-di-iodo-L-thyronine

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7 January 2021

The gene for the RNA component of the mitochondrial RNA-processing endoribonuclease is located on human chromosome 9p and on mouse chromosome 4

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7 January 2021

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

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7 January 2021

Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy

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7 January 2021

An ND-6 mitochondrial DNA mutation associated with Leber hereditary optic neuropathy

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7 January 2021

Cytochrome b mutations in Leber hereditary optic neuropathy

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7 January 2021

Human aging is associated with stochastic somatic mutations of mitochondrial DNA.

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7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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7 January 2021

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

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7 January 2021

Rapid accumulation of deleted mitochondrial deoxyribonucleic acid in postmenopausal ovaries

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7 January 2021

MITOMAP: a human mitochondrial genome database

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7 January 2021

Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family

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7 January 2021

Molecular aspects of isolated and reconstituted carrier proteins from animal mitochondria

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7 January 2021

Fidelity of mammalian DNA polymerases

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7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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7 January 2021

Modulation of membrane phospholipid fatty acid composition by age and food restriction

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7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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7 January 2021

Mutations in mitochondrial tRNA genes: a frequent cause of neuromuscular diseases

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7 January 2021

Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.

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7 January 2021

Three-dimensional structure of NADH: ubiquinone reductase (complex I) from Neurospora mitochondria determined by electron microscopy of membrane crystals

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7 January 2021

Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles

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7 January 2021

Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis

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7 January 2021

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

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7 January 2021

Mitochondrial DNA mutation and the ageing process: bioenergy and pharmacological intervention

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7 January 2021

The development of mitochondrial medicine

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7 January 2021

Import of small RNAs into Leishmania mitochondria in vitro

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7 January 2021

Superoxide dismutase activity of cytochrome oxidase

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7 January 2021

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

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7 January 2021

Mitochondrial changes associated with glutathione deficiency

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7 January 2021

The structure of human mitochondrial DNA variation.

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7 January 2021

Recombination via flanking direct repeats is a major cause of large-scale deletions of human mitochondrial DNA.

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7 January 2021

Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA(Leu(UUR)) gene an etiologic hot spot?

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7 January 2021

Molecular analysis of the muscle pathology associated with mitochondrial DNA deletions

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7 January 2021

A mitochondrial myopathy characterized by a deficiency in reducible cytochrome b.

1 reference

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7 January 2021

In situ hybridization of mitochondrial DNA in the heart of a patient with Kearns-Sayre syndrome and dilatative cardiomyopathy

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7 January 2021

Mitochondria and ageing

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7 January 2021

Clinical aspects of mitochondrial disorders

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7 January 2021

Evidence for increased degeneration of mitochondria in old rats. A brief note

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7 January 2021

How do polypeptides cross the mitochondrial membranes?

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

Carnitine-acylcarnitine translocase deficiency: implications in human pathology

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7 January 2021

Mechanistic and phenomenological features of proton pumps in the respiratory chain of mitochondria.

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7 January 2021

Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications

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7 January 2021

The nuclear-encoded 18 kDa (IP) AQDQ subunit of bovine heart complex I is phosphorylated by the mitochondrial cAMP-dependent protein kinase

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7 January 2021

Age-dependent impairment of mitochondrial function in rat heart tissue. Effect of pharmacological agents

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7 January 2021

The mitochondrial protein import apparatus

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7 January 2021

Mitochondrial import receptors for precursor proteins

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7 January 2021

Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage

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7 January 2021

Families of mtDNA re-arrangements can be detected in patients with mtDNA deletions: duplications may be a transient intermediate form.

1 reference

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7 January 2021

Tandem direct duplications of mitochondrial DNA in mitochondrial myopathy: analysis of nucleotide sequence and tissue distribution.

1 reference

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7 January 2021

Mitochondrial ribosomal RNA mutation associated with both antibiotic–induced and non–syndromic deafness

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7 January 2021

Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Enzyme activity analyses along ragged-red and normal single muscle fibres

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Reactive oxygen and DNA damage in mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Investigation of the essential boundary layer phospholipids of cytochrome c oxidase using Triton X-100 delipidation

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

1 reference

7 January 2021

MITOCHONDRIAL DNA DELETION IN PEARSON'S MARROW/PANCREAS SYNDROME

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https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancy

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https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Characterization of proteins phosphorylated by the cAMP-dependent protein kinase of bovine heart mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

The biochemical basis of mitochondrial diseases

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https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Genetic biochemical and pathophysiological characterization of a familial mitochondrial encephalomyopathy (MERRF)

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Chronic progressive external ophthalmoplegia is associated with a novel mutation in the mitochondrial tRNA(Asn) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Accumulation of deletions in human mitochondrial DNA during normal aging: analysis by quantitative PCR

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

The role of intracellular oxidants in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Protein oxidation and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

An intact protein translocating machinery is required for mitochondrial import of a yeast cytoplasmic tRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitochondrial import of a cytoplasmic lysine-tRNA in yeast is mediated by cooperation of cytoplasmic and mitochondrial lysyl-tRNA synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Phosphorylation of mitochondrial proteins in bovine heart. Characterization of kinases and substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

cAMP-dependent protein phosphorylation in mitochondria of bovine heart

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Persistent oxidative stress in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Energy transduction by cytochrome complexes in mitochondrial and bacterial respiration: the enzymology of coupling electron transfer reactions to transmembrane proton translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Genetics of mitochondrial biogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Conformational changes in oxidized phospholipids and their preferential hydrolysis by phospholipase A2: a monolayer study

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

DNA-protein conjugates can enter mitochondria via the protein import pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitotic segregation of mitochondrial DNAs in human cell hybrids and expression of chloramphenicol resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Sequence analysis of cDNAs for the human and bovine ATP synthase beta subunit: mitochondrial DNA genes sustain seventeen times more mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Diseases of the mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitochondrial DNA mutations in human degenerative diseases and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

The Effect of Age on Mitochondrial Ultrastructure and Enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Mitochondrial respiratory chain inhibitors induce apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Cell death: the significance of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Maternally inherited myopathy and cardiomyopathy: association with mutation in mitochondrial DNA tRNALeu(UUR)

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

An autosomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2896%2900013-1

7 January 2021

10.1016/S0098-2997(96)00013-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9065915%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference