Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists (Q41154685)

27 September 2017

title

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists (English)

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27 September 2017

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Turski L

1

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27 September 2017

Bressler K

2

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27 September 2017

Rettig KJ

3

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27 September 2017

Löschmann PA

4

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27 September 2017

Wachtel H

5

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27 September 2017

language of work or name

English

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publication date

1 January 1991

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27 September 2017

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27 September 2017

volume

349

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27 September 2017

issue

6308

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27 September 2017

page(s)

414-418

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

27 September 2017

cites work

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7 January 2021

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway

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Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

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Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

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L-Glutamate has higher affinity than other amino acids for [3H]-D-AP5 binding sites in rat brain membranes

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2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia

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Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity

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7 January 2021

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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7 January 2021

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

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7 January 2021

Magnesium gates glutamate-activated channels in mouse central neurones

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7 January 2021

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

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7 January 2021

Synaptic activity mediates death of hypoxic neurons

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7 January 2021

The biodisposition of MPP+ in mouse brain

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7 January 2021

Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects

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7 January 2021

Uptake of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and the N-methyl-4-phenylpyridinium ion (MPP+) into fetal mouse brain through the placenta

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7 January 2021

Uptake of a novel anticonvulsant compound, 2-amino-7-phosphono-[4,5-3H]heptanoic acid, into mouse brain

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Determination of the pharmacokinetics of 2-amino-7-phosphonoheptanoate in rat plasma and cerebrospinal fluid

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The histological effects of intracerebral injection or infusion of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and MPP+ (1-methyl-4-phenylpyridinium) in rat and mouse.

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7 January 2021

Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+

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7 January 2021

Ultrastructural alterations induced by 1-methyl-4-phenylpyridinium (MPP+) in canine substantia nigra and rat mesencephalon in vitro

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Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment?

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Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

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NEUROLOGICAL DISEASE IN BOXERS

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7 January 2021

Beta-N-methylamino-L-alanine neurotoxicity: requirement for bicarbonate as a cofactor

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The role of excitatory amino acids and NMDA receptors in traumatic brain injury

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7 January 2021

Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

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7 January 2021

Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels

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7 January 2021

The effect of deprenyl (selegiline) on the natural history of Parkinson's disease

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Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system

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7 January 2021

Identifiers

DOI

10.1038/349414A0

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Dimensions Publication ID

27 September 2017

1005980055

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