Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. (Q40952232)

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scientific article published on June 1999

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English	Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function.	scientific article published on June 1999

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8 December 2019

Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function (English)

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8 December 2019

Michael J. Murray

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M Murray

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8 December 2019

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Y Liu

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8 December 2019

D Kim

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8 December 2019

B T Himes

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8 December 2019

S Y Chow

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8 December 2019

T Schallert

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8 December 2019

A Tessler

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8 December 2019

I Fischer

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8 December 2019

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1 June 1999

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8 December 2019

Journal of Neuroscience

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8 December 2019

19

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8 December 2019

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8 December 2019

4370-4387

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8 December 2019

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Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor.

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Long distance axonal regeneration of identified lamprey reticulospinal neurons

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Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons

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Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells

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Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells.

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Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus

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Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

1 reference

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Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord

1 reference

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Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord

1 reference

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Long axon growth from embryonic neurons transplanted into myelinated tracts of the adult rat spinal cord

1 reference

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Recovery of neurofilament expression selectively in regenerating reticulospinal neurons

1 reference

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12 December 2020

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Regeneration of long spinal axons in the rat

1 reference

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Spinal cord injury in the rat

1 reference

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Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and parkinsonian symptoms

1 reference

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Lesioned corticospinal tract axons regenerate in myelin-free rat spinal cord

1 reference

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Fetal Spinal Cord Transplants Support Growth of Supraspinal and Segmental Projections after Cervical Spinal Cord Hemisection in the Neonatal Rat

1 reference

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Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor

1 reference

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12 December 2020

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Experimental strategies to promote axonal regeneration after traumatic central nervous system injury

1 reference

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Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord

1 reference

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12 December 2020

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Corticospinal tract regrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Restoration of function by replacement of spinal cord segments in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Differential regenerative growth of CNS axons into tibial and peroneal nerve grafts in the thalamus of adult rats.

1 reference

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12 December 2020

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"Exuberant" neuronal growth after brain damage in adult rats: the essential role of behavioral experience

1 reference

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Activated Macrophage/Microglial Cells Can Promote the Regeneration of Sensory Axons into the Injured Spinal Cord

1 reference

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12 December 2020

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NGF enhances neurite regeneration from nerve-transected terminals of young adult and aged mouse dorsal root ganglia in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Regenerated dorsal root fibers form functional synapses in embryonic spinal cord transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Use-dependent growth of pyramidal neurons after neocortical damage.

1 reference

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12 December 2020

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Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts

1 reference

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12 December 2020

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Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats

1 reference

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12 December 2020

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Spinal cord transplants support the regeneration of axotomized neurons after spinal cord lesions at birth: a quantitative double-labeling study

1 reference

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12 December 2020

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Descending nerve tracts in the spinal cord of the rat. I. Fibers from the midbrain

1 reference

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12 December 2020

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Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

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Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

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Peripheral nerve autografts to the rat spinal cord: Studies with axonal tracing methods

1 reference

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12 December 2020

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Physiological relevance and functional potential of central nervous system-derived cell lines

1 reference

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12 December 2020

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Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of Adult Rat Corticospinal Tract by Transplants of Olfactory Ensheathing Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

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Cells of origin, course, and termination patterns of the ventral, uncrossed component of the mature rat corticospinal tract

1 reference

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12 December 2020

based on heuristic

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Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing

1 reference

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12 December 2020

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Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats.

1 reference

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12 December 2020

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Tau-like proteins in the nervous system of goldfish

1 reference

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12 December 2020

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Neurotrophic Factors Increase Axonal Growth after Spinal Cord Injury and Transplantation in the Adult Rat

1 reference

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12 December 2020

based on heuristic

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Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regeneration of brainstem-spinal axons after lesion and immunological disruption of myelin in adult rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of rubrospinal and corticospinal neurons to injury and neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylprednisolone administration improves axonal regeneration into Schwann cell grafts in transected adult rat thoracic spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting genetically modified cells to the brain: possibilities for the future

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long fibre growth by axons of embryonic mouse hippocampal neurons microtransplanted into the adult rat fimbria

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rubrospinal projections in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regeneration of adult axons in white matter tracts of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degeneration and regeneration of axons in the lesioned spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraspinal grafting of fibroblasts genetically modified by recombinant adenoviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafts of fetal central nervous system tissue rescue axotomized Clarke's nucleus neurons in adult and neonatal operates

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF and NT-4/5 Prevent Atrophy of Rat Rubrospinal Neurons after Cervical Axotomy, Stimulate GAP-43 and Tα1-Tubulin mRNA Expression, and Promote Axonal Regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescuing neurons from trans-synaptic degeneration after brain damage: helpful, harmful, or neutral in recovery of function?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use-dependent exaggeration of neuronal injury after unilateral sensorimotor cortex lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Use of Nonneuronal Cells for Gene Delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrovirus packaging cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal transplants alter the development of function after spinal cord transection in newborn rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of recombinant adenovirus for in vivo gene delivery to spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic spinal cord transplants enhance locomotor performance in spinalized newborn rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axon outgrowth from grafts of human embryonic spinal cord in the lesioned adult rat spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10341240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.19-11-04370.1999

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10341240%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10341240%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10341240%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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