Integrin activation: the link between ligand binding and signal transduction (Q40924680)

24 September 2017

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title

Integrin activation: the link between ligand binding and signal transduction (English)

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24 September 2017

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1

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24 September 2017

publication date

1 October 1996

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Current Opinion in Cell Biology

24 September 2017

published in

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24 September 2017

volume

8

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24 September 2017

issue

5

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24 September 2017

page(s)

632-640

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Overview Biologicals and Immunologicals: Integrin antagonists as modulators of adhesion

24 September 2017

cites work

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7 January 2021

Integrins: emerging paradigms of signal transduction

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7 January 2021

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7 January 2021

Integrin transmembrane signaling and cytoskeletal control

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7 January 2021

Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins

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7 January 2021

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

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7 January 2021

Two conformations of the integrin A-domain (I-domain): a pathway for activation?

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7 January 2021

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin

1 reference

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7 January 2021

A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

The A-domain of beta 2 integrin CR3 (CD11b/CD18) is a receptor for the hookworm-derived neutrophil adhesion inhibitor NIF.

1 reference

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7 January 2021

Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18)

1 reference

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7 January 2021

Identification of amino acids in the CD11a I-domain important for binding of the leukocyte function-associated antigen-1 (LFA-1) to intercellular adhesion molecule-1 (ICAM-1)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Critical threonine and aspartic acid residues within the I domains of beta 2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi

1 reference

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7 January 2021

Distinct Ligand Binding Sites in the I Domain of Integrin αMβ2 That Differentially Affect a Divalent Cation-dependent Conformation

1 reference

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7 January 2021

Monoclonal antibodies that block the activity of leukocyte function-associated antigen 1 recognize three discrete epitopes in the inserted domain of CD11a

1 reference

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7 January 2021

A Binding Interface on the I Domain of Lymphocyte Function-associated Antigen-1 (LFA-1) Required for Specific Interaction with Intercellular Adhesion Molecule 1 (ICAM-1)

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7 January 2021

Antibodies That Selectively Inhibit Leukocyte Function-associated Antigen 1 Binding to Intercellular Adhesion Molecule-3 Recognize a Unique Epitope within the CD11a I Domain

1 reference

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7 January 2021

Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit

1 reference

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7 January 2021

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

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7 January 2021

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

1 reference

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7 January 2021

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

1 reference

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7 January 2021

The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Molecular mapping of functional antibody binding sites of alpha 4 integrin

1 reference

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7 January 2021

Critical amino acid residues for ligand binding are clustered in a predicted beta-turn of the third N-terminal repeat in the integrin alpha 4 and alpha 5 subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

A secondary structure model of the integrin alpha subunit N-terminal domain based on analysis of multiple alignments

1 reference

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7 January 2021

Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin

1 reference

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7 January 2021

The amino-terminal one-third of alpha IIb defines the ligand recognition specificity of integrin alpha IIb beta 3.

1 reference

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7 January 2021

Activation of the integrin alpha v beta 3 involves a discrete cation-binding site that regulates conformation

1 reference

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7 January 2021

Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1.

1 reference

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7 January 2021

Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

1 reference

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7 January 2021

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin

1 reference

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7 January 2021

Anchorage dependence, integrins, and apoptosis

1 reference

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7 January 2021

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression

1 reference

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7 January 2021

Alpha 4 beta 1 integrin-dependent cell adhesion is regulated by a low affinity receptor pool that is conformationally responsive to ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Changes in the concentrations of extracellular Mg++ and Ca++ down-regulate E-cadherin and up-regulate alpha 2 beta 1 integrin function, activating keratinocyte migration on type I collagen

1 reference

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7 January 2021

Ca2+ suppresses cell adhesion to osteopontin by attenuating binding affinity for integrin alpha v beta 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Ectopic Expression of Human and Feline CD9 in a Human B Cell Line Confers β1 Integrin-dependent Motility on Fibronectin and Laminin Substrates and Enhanced Tyrosine Phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Specific association of CD63 with the VLA-3 and VLA-6 integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Transendothelial migration of neutrophils involves integrin-associated protein (CD47)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980104-9

7 January 2021

10.1016/S0955-0674(96)80104-9

Identifiers

DOI

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24 September 2017

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