DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis (Q40868557)

24 September 2017

title

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis (English)

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24 September 2017

Thomas DA

1

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24 September 2017

Du C

2

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24 September 2017

Xu M

3

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24 September 2017

Wang X

4

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24 September 2017

Ley TJ

5

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24 September 2017

language of work or name

English

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publication date

1 June 2000

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24 September 2017

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24 September 2017

volume

12

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24 September 2017

issue

6

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24 September 2017

page(s)

621-632

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Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

24 September 2017

cites work

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7 January 2021

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

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7 January 2021

Conversion of the substrate specificity of mouse proteinase granzyme B

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7 January 2021

Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3

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7 January 2021

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

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7 January 2021

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

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7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

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7 January 2021

ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

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7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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7 January 2021

Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation

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7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

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7 January 2021

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

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7 January 2021

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

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7 January 2021

Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1

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7 January 2021

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis

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7 January 2021

Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein

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7 January 2021

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

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7 January 2021

Production of Fully Active Recombinant Murine Granzyme B in Yeast

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7 January 2021

Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A.

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7 January 2021

Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

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7 January 2021

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

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7 January 2021

Caspases: Intracellular Signaling by Proteolysis

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7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

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7 January 2021

Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.

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7 January 2021

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

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7 January 2021

How do cytotoxic lymphocytes kill their targets?

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7 January 2021

Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

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7 January 2021

Substrate specificities of caspase family proteases

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7 January 2021

Granule-mediated killing: pathways for granzyme B-initiated apoptosis.

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7 January 2021

Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis

1 reference

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7 January 2021

CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis

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7 January 2021

Caspases: enemies within

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7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

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7 January 2021

Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980213-7

7 January 2021

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980213-7

7 January 2021

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

1 reference

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7 January 2021

Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45

1 reference

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7 January 2021

DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980213-7

7 January 2021

10.1016/S1074-7613(00)80213-7

Identifiers

DOI

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24 September 2017

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