Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. (Q40758558)

23 September 2017

title

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. (English)

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23 September 2017

Naoya Fujita

1

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23 September 2017

Saori Sato

series ordinal

2

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23 September 2017

Atsushi Ishida

series ordinal

3

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23 September 2017

Takashi Tsuruo

series ordinal

4

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23 September 2017

language of work or name

English

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publication date

4 January 2002

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

issue

12

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23 September 2017

page(s)

10346-10353

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Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating

23 September 2017

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Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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PI3K: downstream AKTion blocks apoptosis

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

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PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

21 January 2018

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Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

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Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

21 January 2018

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Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

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Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

21 January 2018

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Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

21 January 2018

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

21 January 2018

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Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

21 January 2018

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Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily

21 January 2018

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Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin

21 January 2018

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Caspases: killer proteases

21 January 2018

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

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Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway

21 January 2018

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Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

21 January 2018

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

21 January 2018

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The akt kinase: molecular determinants of oncogenicity

21 January 2018

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Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

21 January 2018

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

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Unusual expression and localization of heat-shock proteins in human tumor cells

21 January 2018

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Apoptosis and cancer drug targeting

21 January 2018

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Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

21 January 2018

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Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M106736200

1 reference

23 September 2017

1 reference