E2F modulates keratinocyte squamous differentiation: implications for E2F inhibition in squamous cell carcinoma. (Q40646949)

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3 November 2019

title

E2F modulates keratinocyte squamous differentiation: implications for E2F inhibition in squamous cell carcinoma (English)

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3 November 2019

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8

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3 November 2019

author name string

Chung Fai Wong

1

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3 November 2019

Liam M Barnes

2

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3 November 2019

Alison L Dahler

3

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3 November 2019

Louise Smith

4

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3 November 2019

Magdalena M Serewko-Auret

5

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3 November 2019

Claudia Popa

6

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3 November 2019

Ibtissam Abdul-Jabbar

7

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3 November 2019

language of work or name

English

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publication date

15 May 2003

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Journal of Biological Chemistry

3 November 2019

published in

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3 November 2019

volume

278

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issue

31

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page(s)

28516-28522

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E2F as a Regulator of Keratinocyte Proliferation: Implications for Skin Tumor Development

3 November 2019

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Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids

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E2F-1 induces proliferation-specific genes and suppresses squamous differentiation-specific genes in human epidermal keratinocytes

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Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F

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Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F

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E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

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E2F-4, a new member of the E2F transcription factor family, interacts with p107

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E2F-5, a new E2F family member that interacts with p130 in vivo

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Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6

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E2F-6, a member of the E2F family that can behave as a transcriptional repressor

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E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

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In vivo association of E2F and DP family proteins

21 January 2018

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Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

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Histone deacetylase inhibitors: novel anticancer agents

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The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

21 January 2018

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Cell cycle-specific association of E2F with the p130 E1A-binding protein

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Retinoblastoma protein switches the E2F site from positive to negative element

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p14ARF links the tumour suppressors RB and p53.

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ARF differentially modulates apoptosis induced by E2F1 and Myc.

21 January 2018

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E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

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E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes

21 January 2018

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E2Fs regulate adipocyte differentiation

21 January 2018

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Functional characterization of cultured cells derived from an intraepidermal carcinoma of the skin (IEC-1).

21 January 2018

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Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial

21 January 2018

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Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors expressed in epidermis

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Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

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Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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Suppression of keratinocyte growth and differentiation by transforming growth factor beta1 involves multiple signaling pathways

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

21 January 2018

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Regulation of proliferation-specific and differentiation-specific genes during senescence of human epidermal keratinocyte and mammary epithelial cells

21 January 2018

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Opposite functions for E2F1 and E2F4 in human epidermal keratinocyte differentiation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M301246200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754218%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference