Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors. (Q40613981)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors (English)

1 reference

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26 January 2020

0 references

6

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26 January 2020

author name string

Graham M Pitcher

1

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26 January 2020

Lorraine V Kalia

2

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26 January 2020

David Ng

3

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26 January 2020

Nathalie M Goodfellow

4

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26 January 2020

Kathleen T Yee

5

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26 January 2020

Michael W Salter

7

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26 January 2020

language of work or name

English

0 references

publication date

27 March 2011

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26 January 2020

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26 January 2020

volume

17

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26 January 2020

issue

4

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26 January 2020

page(s)

470-478

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Phenotypic characterization of transgenic mice overexpressing neuregulin-1

26 January 2020

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22 September 2017

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22 September 2017

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Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia

22 September 2017

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Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia

22 September 2017

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PSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complex

22 September 2017

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Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

22 September 2017

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Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia

22 September 2017

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Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

22 September 2017

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The involvement of ErbB4 with schizophrenia: association and expression studies

22 September 2017

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22 September 2017

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The c-Src tyrosine kinase associates with the catalytic domain of ErbB-2: implications for ErbB-2 mediated signaling and transformation.

22 September 2017

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Src kinases: a hub for NMDA receptor regulation

22 September 2017

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22 September 2017

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Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

22 September 2017

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22 September 2017

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Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain

22 September 2017

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NMDA channel regulation by channel-associated protein tyrosine kinase Src.

22 September 2017

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Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo

22 September 2017

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Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation

22 September 2017

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ErbB4 is a suppressor of long-term potentiation in the adult hippocampus

22 September 2017

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Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src.

15 June 2018

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Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses.

15 June 2018

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Association study of neuregulin 1 gene with schizophrenia

15 June 2018

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The role of hippocampus dysfunction in deficient memory encoding and positive symptoms in schizophrenia

15 June 2018

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Cognition in transmembrane domain neuregulin 1 mutant mice

20 August 2018

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20 August 2018

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Neuregulin blocks synaptic strengthening after epileptiform activity in the rat hippocampus

20 August 2018

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Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous 'knockout' of the schizophrenia risk gene neuregulin-1.

20 August 2018

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Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia

20 August 2018

1 reference

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Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

20 August 2018

1 reference

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First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients

20 August 2018

1 reference

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Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex.

20 August 2018

1 reference

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Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia

20 August 2018

1 reference

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Src Activation in the Induction of Long-Term Potentiation in CA1 Hippocampal Neurons

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21441918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21441918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.2315

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

21441918

1 reference