Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. (Q40504219)

21 September 2017

title

Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. (English)

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21 September 2017

Tomomi Kawakatsu

1

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21 September 2017

Hisakazu Ogita

2

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21 September 2017

Tatsuro Fukuhara

3

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21 September 2017

Taihei Fukuyama

4

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21 September 2017

Yukiko Minami

5

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21 September 2017

Kazuya Shimizu

6

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21 September 2017

Yoshimi Takai

7

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21 September 2017

language of work or name

English

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publication date

13 October 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

280

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21 September 2017

issue

6

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21 September 2017

page(s)

4940-4947

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Morphogenetic roles of classic cadherins

21 September 2017

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Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions

21 January 2018

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Regulation of cadherin adhesive activity

21 January 2018

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Molecular architecture of adherens junctions

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Cadherin cell adhesion receptors as a morphogenetic regulator

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Patterning of cell assemblies regulated by adhesion receptors of the cadherin superfamily

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21 January 2018

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Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.

21 January 2018

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Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein

21 January 2018

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Directed actin polymerization is the driving force for epithelial cell-cell adhesion

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Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion

21 January 2018

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Involvement of Nectin-activated Cdc42 Small G Protein in Organization of Adherens and Tight Junctions in Madin-Darby Canine Kidney Cells

21 January 2018

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Trans-interactions of nectins induce formation of filopodia and Lamellipodia through the respective activation of Cdc42 and Rac small G proteins

21 January 2018

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Cadherin engagement regulates Rho family GTPases

21 January 2018

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E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts

21 January 2018

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A novel role of nectins in inhibition of the E-cadherin-induced activation of Rac and formation of cell-cell adherens junctions.

21 January 2018

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Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.

21 January 2018

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Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

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Tyrosine phosphorylation of the vav proto-oncogene product links FcepsilonRI to the Rac1-JNK pathway

21 January 2018

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Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

21 January 2018

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Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

21 January 2018

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Vav2 is required for cell spreading

21 January 2018

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Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.

21 January 2018

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Roles of the Complex Formation of SHPS-1 with SHP-2 in Insulin-stimulated Mitogen-activated Protein Kinase Activation

21 January 2018

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Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

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Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein

21 January 2018

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Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells

21 January 2018

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Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.

21 January 2018

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Regulatory and signaling properties of the Vav family

21 January 2018

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Vav proteins, masters of the world of cytoskeleton organization.

21 January 2018

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Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

21 January 2018

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Vav2 is an activator of Cdc42, Rac1, and RhoA

21 January 2018

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Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins

21 January 2018

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Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

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Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading

21 January 2018

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Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.

21 January 2018

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Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408710200

Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408710200

Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M408710200

1 reference

21 September 2017

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