Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation (Q40498670)

21 September 2017

title

Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation (English)

1 reference

21 September 2017

0 references

endoplasmic reticulum

0 references

Vito Vetrugno

3

0 references

Silvia Biocca

object named as

Silvia Biocca

6

0 references

Maurizio Pocchiari

object named as

Maurizio Pocchiari

4

0 references

author name string

Alessio Cardinale

1

1 reference

21 September 2017

Ilaria Filesi

2

1 reference

21 September 2017

Man-Sun Sy

5

1 reference

21 September 2017

language of work or name

English

0 references

publication date

28 October 2004

1 reference

Journal of Biological Chemistry

21 September 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

21 September 2017

volume

280

1 reference

21 September 2017

issue

1

1 reference

21 September 2017

page(s)

685-694

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

21 September 2017

1 reference

Prions and the lymphoreticular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mammalian prion biology: one century of evolving concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Structural clues to prion replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Separation and properties of cellular and scrapie prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Prion protein conversions: insight into mechanisms, TSE transmission barriers and strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Trafficking, turnover and membrane topology of PrP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Synthesis and trafficking of prion proteins in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Intracellular immunization with cytosolic recombinant antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Characterization of a new intrabody directed against the N-terminal region of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Cloning immunoglobulin variable domains for expression by the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Exploiting recombination in single bacteria to make large phage antibody libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Targeting vectors for intracellular immunisation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

The mode of action of Y13-259 scFv fragment intracellularly expressed in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Intracellular targeting and functional analysis of single-chain Fv fragments in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Prion protein expression in different species: analysis with a panel of new mAbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Guanidine hydrochloride extraction and detection of prion proteins in mouse and hamster prion diseases by ELISA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Novel differences between two human prion strains revealed by two-dimensional gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Further characterization of scrapie replication in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

The selection of intracellular antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Traffic jams II: an update of diseases of intracellular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Aggresomes and Russell bodies. Symptoms of cellular indigestion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Congenital disorders involving defective N-glycosylation of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

21 January 2018

Identifiers

DOI

10.1074/JBC.M407360200

1 reference

21 September 2017

1 reference