20-oxo-5beta-pregnan-3alpha-yl sulfate is a use-dependent NMDA receptor inhibitor. (Q40373481)

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6 January 2020

title

20-oxo-5beta-pregnan-3alpha-yl sulfate is a use-dependent NMDA receptor inhibitor (English)

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6 January 2020

5

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6 January 2020

author name string

Milos Petrovic

1

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6 January 2020

Miloslav Sedlacek

2

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6 January 2020

Martin Horak

3

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6 January 2020

Hana Chodounska

4

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6 January 2020

language of work or name

English

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publication date

1 September 2005

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6 January 2020

published in

Journal of Neuroscience

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6 January 2020

volume

25

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6 January 2020

issue

37

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6 January 2020

page(s)

8439-8450

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The glutamate receptor ion channels

6 January 2020

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Intracellular domains of NR2 alter calcium-dependent inactivation of N-methyl-D-aspartate receptors.

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Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids

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Modal gating of NMDA receptors and the shape of their synaptic response.

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High probability opening of NMDA receptor channels by L-glutamate

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NMDA channel behavior depends on agonist affinity

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Heteromeric NMDA receptors: molecular and functional distinction of subtypes

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The neuroactive steroid 3-alpha-ol-5-beta-pregnan-20-one hemisuccinate, a selective NMDA receptor antagonist improves behavioral performance following spinal cord ischemia

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Synthesis of the sulfates derived from 5 alpha-cholestane-3 beta,6 alpha-diol

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Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity

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A steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivity

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Molecular mechanism of pregnenolone sulfate action at NR1/NR2B receptors.

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Identification of a neurosteroid binding site contained within the GluR2-S1S2 domain

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Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor

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Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action

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Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones

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Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones

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Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

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Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine

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12 December 2020

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels

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Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones

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Ionic Blockage of Sodium Channels in Nerve

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics

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Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

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12 December 2020

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

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12 December 2020

3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons.

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12 December 2020

Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition

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Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9‐aminoacridine

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Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptor

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Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons

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Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors

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Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches

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Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins

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GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systems

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12 December 2020

Patch-clamp recordings from the soma and dendrites of neurons in brain slices using infrared video microscopy

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12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

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12 December 2020

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits

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12 December 2020

NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex.

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12 December 2020

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit

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12 December 2020

Biochemistry by numbers: simulation of biochemical pathways with Gepasi 3

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12 December 2020

Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors

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12 December 2020

N-Terminal Domains in the NR2 Subunit Control Desensitization of NMDA Receptors

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12 December 2020

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

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12 December 2020

Pregnenolone sulfate exacerbates NMDA-induced death of hippocampal neurons

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12 December 2020

Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation

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12 December 2020

10.1523/JNEUROSCI.1407-05.2005

Identifiers

DOI

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6 January 2020

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6 January 2020

PubMed publication ID

16162926

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