Importin KPNA2 is required for proper nuclear localization and multiple functions of NBS1. (Q40368148)

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7 January 2020

title

Importin KPNA2 is required for proper nuclear localization and multiple functions of NBS1 (English)

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7 January 2020

4

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7 January 2020

author name string

Shun-Fu Tseng

series ordinal

1

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7 January 2020

Chun-Yu Chang

series ordinal

2

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7 January 2020

Kou-Juey Wu

series ordinal

3

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7 January 2020

language of work or name

English

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publication date

27 September 2005

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Journal of Biological Chemistry

7 January 2020

published in

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7 January 2020

volume

280

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7 January 2020

issue

47

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7 January 2020

page(s)

39594-39600

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Nijmegen breakage syndrome. The International Nijmegen Breakage Syndrome Study Group

7 January 2020

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Nijmegen breakage syndrome

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Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

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Positional cloning of the gene for Nijmegen breakage syndrome

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The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

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The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

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Positional cloning and functional analysis of the gene responsible for Nijmegen breakage syndrome, NBS1.

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Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

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Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability

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NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

21 January 2018

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ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

21 January 2018

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Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

21 January 2018

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ATM-dependent phosphorylation of nibrin in response to radiation exposure

21 January 2018

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Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation

21 January 2018

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The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

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Transport into and out of the nucleus

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Karyopherins and nuclear import

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Importin alpha transports CaMKIV to the nucleus without utilizing importin beta

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Nucleocytoplasmic protein traffic and its significance to cell function

21 January 2018

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Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

21 January 2018

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A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

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A rapid method for localized mutagenesis of yeast genes

21 January 2018

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Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

21 January 2018

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21 January 2018

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21 January 2018

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Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.

21 January 2018

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Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1

21 January 2018

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The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence

21 January 2018

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Xrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination

21 January 2018

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c-Myc directly regulates the transcription of the NBS1 gene involved in DNA double-strand break repair

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M508425200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16188882%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference