Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins (Q40200987)

From Wikidata

Jump to navigation Jump to search

scientific article published on 4 December 2006

Language	Label	Description	Also known as
English	Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins	scientific article published on 4 December 2006

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

object named as

Bernard Masri

2

0 references

object named as

Herve Prats

5

0 references

object named as

Pavel Krejci

1

0 references

author name string

Lisa Salazar

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Claire Farrington-Rock

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Leslie Michels Thompson

6

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

William R Wilcox

7

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

language of work or name

0 references

publication date

4 December 2006

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

282

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

2929-2936

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

FGF signals for cell proliferation and migration through different pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Protein kinase recognition sequence motifs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Protein kinase C: structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Determination of the specific substrate sequence motifs of protein kinase C isozymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

TPA-induced activation of MAP kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The mitogenic signaling pathway but not the plasminogen activator-inducing pathway of basic fibroblast growth factor is mediated through protein kinase C in fetal bovine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

PKC delta-induced activation of MAPK pathway is required for bFGF-stimulated proliferation of coronary smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Activation of c-fos expression by transforming Ha-ras in HC11 mouse mammary epithelial cells is PKC-dependent and mediated by the serum response element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

FGF receptors ubiquitylation: dependence on tyrosine kinase activity and role in downregulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Sustained ERK1/2 but not STAT1 or 3 activation is required for thanatophoric dysplasia phenotypes in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The Protein-tyrosine-phosphatase SHP2 is phosphorylated on serine residues 576 and 591 by protein kinase C isoforms alpha, beta 1, beta 2, and eta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606144200

21 January 2018

Identifiers

10.1074/JBC.M606144200

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40200987&oldid=1949646109"