Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation (Q40134407)

17 September 2017

title

Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation (English)

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17 September 2017

9

Rose M Cubbon

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15

Andrea Carfi

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17 September 2017

Timothy S Fisher

1

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17 September 2017

Paola Lo Surdo

2

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Shilpa Pandit

3

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Marco Mattu

4

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Joseph C Santoro

5

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Doug Wisniewski

6

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17 September 2017

Richard T Cummings

7

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Alessandra Calzetta

8

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17 September 2017

Paul A Fischer

10

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Anil Tarachandani

11

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17 September 2017

Raffaele De Francesco

12

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17 September 2017

Samuel D Wright

13

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17 September 2017

Carl P Sparrow

14

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Ayesha Sitlani

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17 September 2017

language of work or name

English

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publication date

10 May 2007

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Journal of Biological Chemistry

17 September 2017

published in

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17 September 2017

volume

282

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17 September 2017

issue

28

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17 September 2017

page(s)

20502-20512

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The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

17 September 2017

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Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia

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Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy

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A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

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Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

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Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

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Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells

21 January 2018

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Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

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Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice

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Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

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Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

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Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

21 January 2018

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Recycling receptors: The round-trip itinerary of migrant membrane proteins

21 January 2018

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Structure of the LDL receptor extracellular domain at endosomal pH

21 January 2018

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Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia

21 January 2018

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The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications

21 January 2018

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Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

21 January 2018

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Expression and localization of PCSK9 in rat hepatic cells

21 January 2018

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Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

21 January 2018

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21 January 2018

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ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2

21 January 2018

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Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein

21 January 2018

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The metabolism in vitro of human low-density lipoprotein by the human hepatoma cell line Hep G2

21 January 2018

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The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

21 January 2018

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Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response

21 January 2018

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Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

21 January 2018

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Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M701634200

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17 September 2017

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