Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture (Q40027528)

16 September 2017

title

Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture (English)

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16 September 2017

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Sophie Broussau

1

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16 September 2017

Nadine Jabbour

2

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16 September 2017

Guillaume Lachapelle

3

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16 September 2017

Yves Durocher

4

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16 September 2017

Rosanne Tom

5

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16 September 2017

Julia Transfiguracion

6

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16 September 2017

Rénald Gilbert

7

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16 September 2017

Bernard Massie

8

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16 September 2017

publication date

8 January 2008

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16 September 2017

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16 September 2017

volume

16

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16 September 2017

issue

3

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16 September 2017

page(s)

500-507

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describes a project that uses

16 September 2017

HEK293SF-PacLV

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cites work

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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7 January 2021

Efficient gene transfer by a human immunodeficiency virus type 1 (HIV-1)-derived vector utilizing a stable HIV packaging cell line

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Generation of a flexible cell line with regulatable, high-level expression of HIV Gag/Pol particles capable of packaging HIV-derived vectors

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7 January 2021

A stable system for the high-titer production of multiply attenuated lentiviral vectors

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

An inducible packaging cell system for safe, efficient lentiviral vector production in the absence of HIV-1 accessory proteins

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

A new-generation stable inducible packaging cell line for lentiviral vectors

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Continuous high-titer HIV-1 vector production.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

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7 January 2021

The cumate gene-switch: a system for regulated expression in mammalian cells

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7 January 2021

A third-generation lentivirus vector with a conditional packaging system

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Robust and efficient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Certification assays for HIV-1-based vectors: frequent passage of gag sequences without evidence of replication-competent viruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Size-exclusion chromatography purification of high-titer vesicular stomatitis virus G glycoprotein-pseudotyped retrovectors for cell and gene therapy applications

1 reference

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7 January 2021

Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Factors influencing the titer and infectivity of lentiviral vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Optimisation of a multipartite human immunodeficiency virus based vector system; control of virus infectivity and large-scale production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Retroviral vector production using suspension-adapted 293GPG cells in a 3L acoustic filter-based perfusion bioreactor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

A gene that encodes a product with similarity to dioxygenases is highly expressed in teliospores of Ustilago maydis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Highly efficient transfection of mammalian cells by electric field pulses. Application to large volumes of cell culture by using a flow system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

A selectable bifunctional β-galactosidase::phleomycin-resistance fusion protein as a potential marker for eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

PABPN1 overexpression leads to upregulation of genes encoding nuclear proteins that are sequestered in oculopharyngeal muscular dystrophy nuclear inclusions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Inducible Overexpression of a Toxic Protein by an Adenovirus Vector with a Tetracycline-Regulatable Expression Cassette

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Development of a self-inactivating lentivirus vector.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Culture of insect cells in helical ribbon impeller bioreactor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Large-scale transient transfection of serum-free suspension-growing HEK293 EBNA1 cells: peptone additives improve cell growth and transfection efficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300383

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300383

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16 September 2017

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