Multiple sclerosis: glatiramer acetate induces anti-inflammatory T cells in the cerebrospinal fluid. (Q39963593)

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10 January 2020

title

Multiple sclerosis: glatiramer acetate induces anti-inflammatory T cells in the cerebrospinal fluid (English)

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10 January 2020

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3

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10 January 2020

author name string

A L K Hestvik

1

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10 January 2020

G Skorstad

2

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10 January 2020

F Vartdal

4

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10 January 2020

T Holmoy

5

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10 January 2020

publication date

1 July 2008

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Multiple Sclerosis Journal

10 January 2020

published in

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10 January 2020

volume

14

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10 January 2020

issue

6

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10 January 2020

page(s)

749-758

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Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

10 January 2020

cites work

1 reference

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Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group

21 January 2018

1 reference

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Glatiramer acetate reduces lymphocyte proliferation and enhances IL-5 and IL-13 production through modulation of monocyte-derived dendritic cells in multiple sclerosis

21 January 2018

1 reference

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Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

21 January 2018

1 reference

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Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

21 January 2018

1 reference

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Glatiramer acetate: mechanisms of action in multiple sclerosis

21 January 2018

1 reference

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Sustained immunological effects of Glatiramer acetate in patients with multiple sclerosis treated for over 6 years

21 January 2018

1 reference

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Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis

21 January 2018

1 reference

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Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells

21 January 2018

1 reference

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Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis

21 January 2018

1 reference

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Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1

21 January 2018

1 reference

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Oral treatment of mice with copolymer 1 (glatiramer acetate) results in the accumulation of specific Th2 cells in the central nervous system

21 January 2018

1 reference

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Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain-derived neurotrophic factor

21 January 2018

1 reference

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T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: possible therapy for optic neuropathies

21 January 2018

1 reference

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Glatiramer acetate-reactive T cells produce brain-derived neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factorin situ

21 January 2018

1 reference

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Inflammatory potential and migratory capacities across human brain endothelial cells of distinct glatiramer acetate-reactive T cells generated in treated multiple sclerosis patients.

21 January 2018

1 reference

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Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Cerebrospinal fluid CD4+ T cells from a multiple sclerosis patient cross-recognize Epstein-Barr virus and myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

21 January 2018

1 reference

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Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells

21 January 2018

1 reference

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T(H)-17 cells in the circle of immunity and autoimmunity

21 January 2018

1 reference

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Glatiramer acetate (copolymer-1)-specific, human T cell lines: cytokine profile and suppression of T cell lines reactive against myelin basic protein

21 January 2018

1 reference

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Human cellular immune response to copolymer I and myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Human and murine CD4 T cell reactivity to a complex antigen: recognition of the synthetic random polypeptide glatiramer acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Glatiramer acetate (GA) therapy induces a focused, oligoclonal CD8+ T-cell repertoire in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

CDR3 loop flexibility contributes to the degeneracy of TCR recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1352458508089411

21 January 2018

Identifiers

DOI

10.1177/1352458508089411

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18611988%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference