VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease. (Q39784491)

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scientific article published on 20 October 2009

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English	VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease.	scientific article published on 20 October 2009

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scholarly article

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10 February 2020

VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease (English)

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10 February 2020

Caenorhabditis elegans

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Parkinson's disease

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based on heuristic

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David G. Standaert

5

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10 February 2020

Adam J Harrington

2

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10 February 2020

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object named as

Guy A Caldwell

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10 February 2020

author name string

Qingmin Ruan

1

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10 February 2020

Kim A Caldwell

3

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10 February 2020

publication date

20 October 2009

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10 February 2020

Neurobiology of Disease

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10 February 2020

37

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10 February 2020

2

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10 February 2020

330-338

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10 February 2020

Molecular participants in mitochondrial cell death channel formation during neuronal ischemia

1 reference

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Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

1 reference

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22 September 2017

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

1 reference

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Genomic investigation of alpha-synuclein multiplication and parkinsonism

1 reference

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

1 reference

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Disease-modifying pathways in neurodegeneration.

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22 September 2017

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

1 reference

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

1 reference

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22 September 2017

Toxin-induced models of Parkinson's disease

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6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta

1 reference

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22 September 2017

Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10.

1 reference

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22 September 2017

Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae

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22 September 2017

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

1 reference

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Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration

1 reference

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22 September 2017

Effects of 6-hydroxydopamine on primary cultures of substantia nigra: specific damage to dopamine neurons and the impact of glial cell line-derived neurotrophic factor

1 reference

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22 September 2017

Mechanism of toxicity in rotenone models of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818321

22 September 2017

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

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22 September 2017

Caspase-3-mediated cleavage of Rad9 during apoptosis

1 reference

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22 September 2017

Parkinson's disease: mechanisms and models

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22 September 2017

The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration

1 reference

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22 September 2017

Neuroprotective and neurorestorative strategies for Parkinson's disease

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Mitochondrial involvement in the point of no return in neuronal apoptosis

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Mechanisms of caspase activation and inhibition during apoptosis

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22 September 2017

Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

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22 September 2017

Complex I and Parkinson's disease

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22 September 2017

Alpha-synuclein and neurodegenerative diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818321

22 September 2017

hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif

1 reference

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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

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Formation of AP-3 transport intermediates requires Vps41 function

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Etiology and pathogenesis of Parkinson's disease

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α-Synuclein in Lewy bodies

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19850127

12 December 2020

based on heuristic

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Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19850127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NBD.2009.10.011

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19850127%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PMC publication ID

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Europe PubMed Central

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10 February 2020

PubMed publication ID

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Europe PubMed Central

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10 February 2020

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