N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells. (Q39653761)

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14 February 2020

title

N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells (English)

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14 February 2020

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2

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Tuomas Mirtti

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author name string

Ayush Dagvadorj

1

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Zhiyong Liao

3

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Jianwu Xie

4

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14 February 2020

Martti Nurmi

5

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Kalle Alanen

6

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Hallgeir Rui

7

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Marja T Nevalainen

9

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publication date

18 September 2010

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International Journal of Biochemistry & Cell Biology

14 February 2020

published in

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volume

42

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issue

12

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page(s)

2037-2046

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Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth.

14 February 2020

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo

14 September 2017

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14 September 2017

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

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A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

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Differential PIAS3 expression in human malignancy

14 September 2017

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Expression of androgen receptor coregulators in prostate cancer

14 September 2017

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PIAS/SUMO: new partners in transcriptional regulation.

14 September 2017

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Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer

14 September 2017

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Stats: transcriptional control and biological impact

14 September 2017

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Signaling through the JAK/STAT pathway, recent advances and future challenges

14 September 2017

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The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer

14 September 2017

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PRL signal transduction in the epithelial compartment of rat prostate maintained as long-term organ cultures in vitro

14 September 2017

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Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells

14 September 2017

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The Stat family in cytokine signaling

14 September 2017

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The significance of tetramerization in promoter recruitment by Stat5.

14 September 2017

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

14 September 2017

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Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

14 September 2017

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STATs and Gene Regulation

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Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway

14 September 2017

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14 September 2017

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Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells

14 September 2017

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14 September 2017

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12 December 2020

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12 December 2020

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Identifiers

DOI

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14 February 2020

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14 February 2020

PubMed publication ID

20854925

1 reference