Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. (Q39539847)

12 September 2017

Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. (English)

1 reference

12 September 2017

Vaccinia virus

1 reference

Marc Kvansakul

3

0 references

author name string

Stephanie Campbell

1

1 reference

12 September 2017

Bart Hazes

2

1 reference

12 September 2017

Peter Colman

4

1 reference

12 September 2017

Michele Barry

5

1 reference

12 September 2017

language of work or name

English

0 references

publication date

2 December 2009

1 reference

Journal of Biological Chemistry

12 September 2017

1 reference

12 September 2017

285

1 reference

12 September 2017

7

1 reference

12 September 2017

4695-4708

1 reference

describes a project that uses

12 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2836074/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

13 September 2017

1 reference

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

13 September 2017

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A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

13 September 2017

1 reference

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Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

13 September 2017

1 reference

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

13 September 2017

1 reference

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The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

13 September 2017

1 reference

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A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

13 September 2017

1 reference

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13 September 2017

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Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins

13 September 2017

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13 September 2017

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The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Vaccinia virus infection disarms the mitochondrion-mediated pathway of the apoptotic cascade by modulating the permeability transition pore

14 September 2017

1 reference

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The genome of fowlpox virus

14 September 2017

1 reference

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Ectromelia virus encodes a novel family of F-box proteins that interact with the SCF complex

14 September 2017

1 reference

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Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Puma(*)Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Myxoma virus M11L prevents apoptosis through constitutive interaction with Bak.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Inhibition of apoptosis by the African swine fever virus Bcl-2 homologue: role of the BH1 domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

The target DNA sequence for resolution of poxvirus replicative intermediates is an active late promoter.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Vaccinia virus F1L protein is a tail-anchored protein that functions at the mitochondria to inhibit apoptosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Interaction of E1B 19K with Bax is required to block Bax-induced loss of mitochondrial membrane potential and apoptosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Fowlpox virus encodes a Bcl-2 homologue that protects cells from apoptotic death through interaction with the proapoptotic protein Bak.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

BHRF1, a viral homologue of the Bcl-2 oncogene, is conserved at both the sequence and functional level in different Epstein-Barr virus isolates

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Establishment of monoclonal anti-Nk-1.1 antibody.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836074

Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19955184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19955184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.053769

1 reference

release_zxvlx5imffb4pao2eqccwhhzci

12 September 2017

0 references

1 reference

12 September 2017

PubMed publication ID

19955184

1 reference