Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. (Q39361900)

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English	Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.	scientific article

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29 January 2020

Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death (English)

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Europe PubMed Central

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29 January 2020

telomere length

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acute myeloid leukemia

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based on heuristic

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Irene Maeve Rea

5

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29 January 2020

8

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29 January 2020

Kerry Pettigrew

1

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29 January 2020

Richard N. Armstrong

2

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29 January 2020

4

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29 January 2020

7

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29 January 2020

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Hilary A A Colyer

3

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29 January 2020

Rhiannon E Jones

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29 January 2020

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19 April 2012

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29 January 2020

Genes, Chromosomes and Cancer

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29 January 2020

51

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29 January 2020

8

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29 January 2020

768-780

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29 January 2020

The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

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Cytosine methylation in CTF and Sp1 recognition sites of an HSV tk promoter: effects on transcription in vivo and on factor binding in vitro

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DNA methylation patterns and epigenetic memory

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The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

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Concise review: Telomere biology in normal and leukemic hematopoietic stem cells

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5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

1 reference

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Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia

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Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.

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Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells

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Identification and characterization of a family of mammalian methyl-CpG binding proteins

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DNMT3A Mutations in Acute Myeloid Leukemia

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Detection of telomerase activity and the expression of telomerase subunits in the patients with acute myelogenous leukaemia

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Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.

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A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

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The proto-oncogene BCL-6 is expressed in olfactory sensory neurons

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Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines

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CTCF binds the proximal exonic region of hTERT and inhibits its transcription

1 reference

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5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.

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Methylation inhibitor therapy in the treatment of myelodysplastic syndrome

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Verification of complete bisulfite modification using Calponin-specific primer sets

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The 5-lipoxygenase promoter is regulated by DNA methylation

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5-Aza-2'-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis

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Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

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hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site

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1 reference

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