Significance of resistance of herpes simplex virus to acyclovir. (Q39174061)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2828441%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

review article

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title

Significance of resistance of herpes simplex virus to acyclovir (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2828441%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

author name string

C S Crumpacker

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2828441%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

language of work or name

English

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publication date

1 January 1988

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Journal of the American Academy of Dermatology

5 October 2019

published in

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5 October 2019

volume

18

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5 October 2019

issue

1 Pt 2

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5 October 2019

page(s)

190-195

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Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine

5 October 2019

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Susceptibility to other antiherpes drugs of pathogenic variants of herpes simplex virus selected for resistance to acyclovir

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Virus drug-resistance: mechanisms and consequences

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The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice

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Trigeminal Ganglion Infection by Thymidine Kinase-Negative Mutants of Herpes Simplex Virus

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7 January 2021

Intracerebral Inoculation of Newborn and Adult Mice with Thymidine Kinase-Deficient Mutants of Herpes Simplex Virus Type 1

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7 January 2021

Acute and latent infection by thymidine kinase mutants of herpes simplex virus type 2.

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7 January 2021

A perspective on resistance to acyclovir in herpes simplex virus

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7 January 2021

Suppression of frequently recurring genital herpes. A placebo-controlled double-blind trial of oral acyclovir

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Clinical isolate of herpes simplex virus type 2 that induces a thymidine kinase with altered substrate specificity

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7 January 2021

Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus

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7 January 2021

Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine

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Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene

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7 January 2021

Herpes simplex virus variants restraint to high concentrations of acyclovir exist in clinical isolates

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7 January 2021

Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance

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7 January 2021

Resistance of herpes simplex virus to adenine arabinoside and E-5-(2-bromovinyl)-2'-deoxyuridine: a physical analysis

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7 January 2021

Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci

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7 January 2021

In Vitro Sensitivity to Acyclovir in Genital Herpes Simplex Viruses from Acyclovir-Treated Patients

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7 January 2021

Resistance to antiviral drugs of herpes simplex virus isolated from a patient treated with acyclovir

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7 January 2021

A colorimetric assay for the measurement of the sensitivity of herpes simplex viruses to antiviral agents

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7 January 2021

Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates

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7 January 2021

Comparative methods for detection of thymidine kinase-deficient herpes simplex virus type 1 strains

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7 January 2021

A comparison of the antiviral agents 2′-nor-2′-deoxyguanosine and acyclovir: Uptake and phosphorylation in tissue culture and kinetics of in vitro inhibition of viral and cellular DNA polymerases by their respective triphosphates

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7 January 2021

Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine

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7 January 2021

Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1

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7 January 2021

Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U

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7 January 2021

Treatment of cytomegalovirus retinitis with 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine

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7 January 2021

Effect of 9-(1,3-dihydroxy-2-propoxymethyl) guanine on serious cytomegalovirus disease in eight immunosuppressed homosexual men

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7 January 2021

Treatment of serious cytomegalovirus infections with 9-(1,3-dihydroxy-2-propoxymethyl)guanine in patients with AIDS and other immunodeficiencies

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7 January 2021

Differential effects of acyclovir and 9-(1,3-dihydroxy-2-propoxymethyl)guanine on herpes simplex virus and Epstein-Barr virus in a dually infected human lymphoblastoid cell line

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7 January 2021

2'-Nor-2'-deoxyguanosine is an effective therapeutic agent for treatment of experimental herpes keratitis

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7 January 2021

Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information

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7 January 2021

Inhibition of HSV-transformed murine cells by nucleoside analogs, 2'-NDG and 2'-nor-cGMP: mechanisms of inhibition and reversal by exogenous nucleosides

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7 January 2021

2'-Nor-cGMP: a seco-cyclic nucleotide with powerful anti-DNA-viral activity

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7 January 2021

Comparison of the modes of antiviral action of 2'-nor-deoxyguanosine and its cyclic phosphate, 2'-nor-cyclic GMP.

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7 January 2021

Selective inhibitory effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 2'-nor-cyclic GMP on adenovirus replication in vitro

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7 January 2021

Recurrent genital herpes and suppressive oral acyclovir therapy. Relation between clinical outcome and in-vitro drug sensitivity.

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7 January 2021

Prophylaxis: a strategy to minimise antiviral resistance

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7 January 2021

Virus resistance in clinical practice

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7 January 2021

Pathogenicity of acyclovir-resistant herpes simplex virus type 1 from an immunodeficient child

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7 January 2021

Frequency and significance of acyclovir-resistant herpes simplex virus isolated from marrow transplant patients receiving multiple courses of treatment with acyclovir

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7 January 2021

Characterization of acyclovir-resistant and -sensitive herpes simplex viruses isolated from a patient with an acquired immune deficiency.

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7 January 2021

10.1016/S0190-9622(88)70026-2

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2828441%20AND%20SRC:MED&resulttype=core&format=json

5 October 2019

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