Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways. (Q39172323)

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27 February 2020

title

Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways (English)

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3

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author name string

Qihui Li

1

1 reference

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27 February 2020

Lei Huai

2

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27 February 2020

Cuicui Wang

4

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27 February 2020

Yujjao Jia

5

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27 February 2020

Yirui Chen

6

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27 February 2020

Pei Yu

7

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27 February 2020

Houcai Wang

8

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27 February 2020

Qing Rao

9

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27 February 2020

Min Wang

10

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27 February 2020

Jianxiang Wang

11

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27 February 2020

publication date

3 April 2013

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International Journal of Hematology

27 February 2020

published in

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volume

97

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issue

5

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page(s)

617-623

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The clinical development of FLT3 inhibitors in acute myeloid leukemia

27 February 2020

cites work

1 reference

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Inducible effects of icariin, icaritin, and desmethylicaritin on directional differentiation of embryonic stem cells into cardiomyocytes in vitro

21 January 2018

1 reference

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Neuroprotective effects of icaritin against beta amyloid-induced neurotoxicity in primary cultured rat neuronal cells via estrogen-dependent pathway.

21 January 2018

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An anticancer agent icaritin induces sustained activation of the extracellular signal-regulated kinase (ERK) pathway and inhibits growth of breast cancer cells

21 January 2018

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Proliferation-stimulating effects of icaritin and desmethylicaritin in MCF-7 cells

21 January 2018

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Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells

21 January 2018

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Icaritin induces apoptosis of HepG2 cells via the JNK1 signaling pathway independent of the estrogen receptor

21 January 2018

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Icaritin Shows Potent Anti-Leukemia Activity on Chronic Myeloid Leukemia In Vitro and In Vivo by Regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT Signalings

21 January 2018

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Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia

21 January 2018

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Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo

21 January 2018

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Deregulation of apoptosis in acute myeloid leukemia

21 January 2018

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Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae

21 January 2018

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The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells

21 January 2018

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Apoptotic signaling by c-MYC.

21 January 2018

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Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines.

21 January 2018

1 reference

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Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.

21 January 2018

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Cytotoxic effect and apoptotic mechanism of tanshinone A, a novel tanshinone derivative, on human erythroleukemic K562 cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23550021

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Acute myeloid leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23550021

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12185-013-1317-9

1 reference

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27 February 2020

1 reference