Direct inhibition of retinoblastoma phosphorylation by nimbolide causes cell-cycle arrest and suppresses glioblastoma growth. (Q39068923)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170547%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Direct inhibition of retinoblastoma phosphorylation by nimbolide causes cell-cycle arrest and suppresses glioblastoma growth (English)

1 reference

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28 February 2020

1 reference

1 reference

1 reference

11

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28 February 2020

author name string

Swagata Karkare

1

1 reference

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28 February 2020

Rishi Raj Chhipa

2

1 reference

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28 February 2020

Jane Anderson

3

1 reference

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28 February 2020

Xiaona Liu

4

1 reference

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28 February 2020

Heather Henry

5

1 reference

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28 February 2020

Anjelika Gasilina

6

1 reference

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28 February 2020

Nicholas Nassar

7

1 reference

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28 February 2020

Jayeeta Ghosh

8

1 reference

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28 February 2020

Jason P Clark

9

1 reference

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28 February 2020

Ashish Kumar

10

1 reference

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28 February 2020

Pradip K Ghosh

12

1 reference

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28 February 2020

Biplab Dasgupta

13

1 reference

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28 February 2020

language of work or name

English

0 references

publication date

29 October 2013

1 reference

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28 February 2020

published in

Clinical Cancer Research

1 reference

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28 February 2020

volume

20

1 reference

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28 February 2020

issue

1

1 reference

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28 February 2020

page(s)

199-212

1 reference

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CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009.

28 February 2020

cites work

1 reference

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Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis

9 September 2017

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Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents

9 September 2017

1 reference

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Medicinal properties of fractionated acetone/water neem [Azadirachta indica] leaf extract from Nigeria: a review.

9 September 2017

1 reference

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AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development

9 September 2017

1 reference

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Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model

9 September 2017

1 reference

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Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas

9 September 2017

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Cancer chemoprevention through dietary antioxidants: progress and promise

9 September 2017

1 reference

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Expression of PCNA, cytokeratin, Bcl-2 and p53 during chemoprevention of hamster buccal pouch carcinogenesis by ethanolic neem (Azadirachta indica) leaf extract

9 September 2017

1 reference

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Inhibition of survival signalling by dietary polyphenols and indole-3-carbinol

9 September 2017

1 reference

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Medicinal properties of neem leaves: a review

9 September 2017

1 reference

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Malignant glioma: genetics and biology of a grave matter.

9 September 2017

1 reference

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

9 September 2017

1 reference

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Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.

9 September 2017

1 reference

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

9 September 2017

1 reference

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The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells

9 September 2017

1 reference

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Nimbolide a limonoid from Azadirachta indica inhibits proliferation and induces apoptosis of human choriocarcinoma (BeWo) cells

14 September 2017

1 reference

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Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells

14 September 2017

1 reference

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Antiproliferative effect on human cancer cell lines after treatment with nimbolide extracted from an edible part of the neem tree (Azadirachta indica).

14 September 2017

1 reference

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Synthesis and biological activity of amide derivatives of nimbolide

14 September 2017

1 reference

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An antimalarial extract from neem leaves is antiretroviral

14 September 2017

1 reference

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Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

14 September 2017

1 reference

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p53 modulation of anchorage independent growth and experimental metastasis.

25 September 2017

1 reference

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Protein tyrosine kinase receptors

25 September 2017

1 reference

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Cytotoxicity of nimbolide, epoxyazadiradione and other limonoids from neem insecticide

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947304

Insect antifeedant activity of tetranortriterpenoids from the Rutales. A perusal of structural relations

25 September 2017

1 reference

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Nimbolide, a constituent of Azadirachta indica, inhibits Plasmodium falciparum in culture

17 June 2018

1 reference

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The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral oncogenesis.

17 June 2018

1 reference

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Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21.

21 August 2018

1 reference

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CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated.

21 August 2018

1 reference

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Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

21 August 2018

1 reference

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Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24170547

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Possible biochemical mode of anti-inflammatory action of Azadirachta indica A. Juss. in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24170547

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nimbolide is the Principal Cytotoxic Component of Neem-Seed Insecticide Preparations

0 references

Identifiers

DOI

10.1158/1078-0432.CCR-13-0762

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170547%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170547%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

24170547

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170547%20AND%20SRC:MED&resulttype=core&format=json