Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion. (Q38976962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25007006%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion (English)

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9 March 2020

6

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9 March 2020

author name string

Shilong Zheng

1

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9 March 2020

Qiu Zhong

2

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9 March 2020

Yulan Xi

3

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9 March 2020

Madhusoodanan Mottamal

4

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9 March 2020

Qiang Zhang

5

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9 March 2020

Jayalakshmi Sridhar

7

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9 March 2020

Ling He

8

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9 March 2020

Harris McFerrin

9

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9 March 2020

Guangdi Wang

10

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9 March 2020

language of work or name

English

0 references

publication date

18 July 2014

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Journal of Medicinal Chemistry

9 March 2020

published in

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9 March 2020

volume

57

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9 March 2020

issue

15

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9 March 2020

page(s)

6653-6667

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Regulation of angiogenesis via Notch signaling in breast cancer and cancer stem cells

9 March 2020

cites work

1 reference

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A cell-based fascin bioassay identifies compounds with potential anti-metastasis or cognition-enhancing functions.

9 September 2017

1 reference

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Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma.

9 September 2017

1 reference

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Fascin Is a Key Regulator of Breast Cancer Invasion That Acts via the Modification of Metastasis-Associated Molecules

9 September 2017

1 reference

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Filopodia and adhesion in cancer cell motility

9 September 2017

1 reference

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Mechanism of Actin Filament Bundling by Fascin

9 September 2017

1 reference

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The roles of fascins in health and disease

9 September 2017

1 reference

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Fascin: a key regulator of cytoskeletal dynamics

9 September 2017

1 reference

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Migrastatin analogues target fascin to block tumour metastasis

9 September 2017

1 reference

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Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer

9 September 2017

1 reference

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Expression of fascin-1, an actin-bundling protein, in migrating hepatoblasts during rat liver development

9 September 2017

1 reference

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The role of fascin in the migration and invasiveness of malignant glioma cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136724

Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer

9 September 2017

1 reference

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Multifaceted role of Rho proteins in angiogenesis

9 September 2017

1 reference

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Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression

9 September 2017

1 reference

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Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

9 September 2017

1 reference

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Amino-aromatic interactions in proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136724

The role of fascin in migration and invasion of urothelial carcinoma of the bladder

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136724

Fascin 1 is dispensable for developmental and tumour angiogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136724

Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136724

The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136724

Independent value of fascin immunoreactivity for predicting lymph node metastases in typical and atypical pulmonary carcinoids.

21 August 2018

1 reference

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Planar stacking interactions of arginine and aromatic side-chains in proteins

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25007006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM500724X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25007006%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

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9 March 2020

PubMed publication ID

25007006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25007006%20AND%20SRC:MED&resulttype=core&format=json