Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes (Q38934642)

7 September 2017

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title

Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes (English)

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7 September 2017

Jinyun Dong

1

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7 September 2017

Qijing Zhang

2

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7 September 2017

Qing Cui

3

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7 September 2017

Guang Huang

4

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7 September 2017

Xiaoyan Pan

5

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7 September 2017

Shaoshun Li

6

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7 September 2017

publication date

23 August 2016

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7 September 2017

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7 September 2017

volume

11

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7 September 2017

issue

19

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7 September 2017

page(s)

2102-2118

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Structural Characterization of the Complex between α-Naphthoflavone and Human Cytochrome P450 1B1

7 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Discovery of cytochrome P450 1B1 inhibitors as new promising anti-cancer agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 1 family and cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

The aryl hydrocarbon receptor in anticancer drug discovery: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Extra-hepatic isozymes from the CYP1 and CYP2 families as potential chemotherapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 family 1 inhibitors and structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Insights into the structure, function, and regulation of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 CYP1B1 protein expression: a novel mechanism of anticancer drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 1B1: a novel anticancer therapeutic target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Binding of 2-hydroxyestradiol and 4-hydroxyestradiol to estrogen receptors from human breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Catecholestrogens are MCF-7 cell estrogen receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Tumour cytochrome P450 and drug activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

CYP1B1, a developmental gene with a potential role in glaucoma therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 1B1 contributes to angiotensin II-induced hypertension and associated pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition and inactivation of murine hepatic ethoxy- and pentoxyresorufin O-dealkylase by naturally occurring coumarins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of cytochrome p450 enzymes by quinones and anthraquinones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Soy isoflavones and virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Simultaneous determination of all polyphenols in vegetables, fruits, and teas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Flavonoids as antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibitors and prodrugs targeting CYP1: a novel approach in cancer prevention and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Selective inhibition of methoxyflavonoids on human CYP1B1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of 7-ethoxycoumarinO-deethylase activity in rat liver microsomes by naturally occurring flavonoids: structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Development of flavone propargyl ethers as potent and selective inhibitors of cytochrome P450 enzymes 1A1 and 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Effects of hydroxyl group numbers on the B-ring of 5,7-dihydroxyflavones on the differential inhibition of human CYP 1A and CYP1B1 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Ethynylflavones, highly potent, and selective inhibitors of cytochrome P450 1A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

A study on CYP1A inhibitory action of E-2-(4'-methoxybenzylidene)-1-benzosuberone and some related chalcones and cyclic chalcone analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Flavonoids and other compounds from Ouratea ferruginea (Ochnaceae) as anticancer and chemopreventive agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Metabolites of galangin by 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P450 1A1 in human intestinal epithelial Caco-2 cells and their antagonistic activity toward aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

The methoxylated flavones eupatorin and cirsiliol induce CYP1 enzyme expression in MCF7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of extrahepatic human cytochromes P450 1A1 and 1B1 by metabolism of isoflavones found in Trifolium pratense (red clover).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Hop (Humulus lupulus L.) extract and 6-prenylnaringenin induce P450 1A1 catalyzed estrogen 2-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Endogenous and exogenous ligands of aryl hydrocarbon receptor: current state of art.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

In vitro activation of the dioxin receptor to a DNA-binding form by food-borne heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Structure-activity relationships of the 7-substituents of 5,4'-diamino-6,8,3'-trifluoroflavone, a potent antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Novel 5-aminoflavone derivatives as specific antitumor agents in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Synergistic interactions between aminoflavone, paclitaxel and camptothecin in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Interference of glucocorticoids with apoptosis signaling and host-tumor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Activation of the antitumor agent aminoflavone (NSC 686288) is mediated by induction of tumor cell cytochrome P450 1A1/1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of human estrogen synthetase (aromatase) by flavones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

alpha-Naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Naphthoflavones as Antiproliferative Agents: Design, Synthesis and Biological Evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

The systemic and gonadal toxicity of 3-methylcholanthrene is prevented by daily administration of α-naphthoflavone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Tight-binding inhibition by alpha-naphthoflavone of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

The effect of beta-naphthoflavone on the metabolism of amiodarone by hepatic and extra-hepatic microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Inhibition of aromatase cytochrome P-450 (estrogen synthetase) by derivatives of alpha-naphthoflavone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

A 3D model of CYP1B1 explains the dominant 4-hydroxylation of estradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

A preliminary structure-activity study of the mixed-function oxidase inhibitor, 7,8-benzoflavone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Cancer Activation and Polymorphisms of Human Cytochrome P450 1B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

5-(3-Hydroxymethyl-3-methyl-1-triazeno imidazole-4-carboxamide is a metabolite of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DIC, DTIC NSC-45388).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

21 January 2018

New uses for old drugs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Fluvoxamine-theophylline interaction: gap between in vitro and in vivo inhibition constants toward cytochrome P4501A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Clinical implications of drug-drug interactions with P2Y12 receptor inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Isolation, biological activity and synthesis of the natural product ellipticine and related pyridocarbazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

Molecular characteristics of catechol estrogen quinones in reactions with deoxyribonucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

7 January 2021

Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

7 January 2021

Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

7 January 2021

Inhibition of methoxyresorufin demethylase activity by flavonoids in human liver microsomes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

7 January 2021

Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600316

7 January 2021

Identifiers

DOI

10.1002/CMDC.201600316

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/q26ecvpzxvcrxk2fwz3ioqjhfm

30 July 2022

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Fatcat ID

release_q26ecvpzxvcrxk2fwz3ioqjhfm

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Fatcat

https://api.fatcat.wiki/v0/release/q26ecvpzxvcrxk2fwz3ioqjhfm

30 July 2022

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https://api.fatcat.wiki/v0/release/q26ecvpzxvcrxk2fwz3ioqjhfm

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30 July 2022