Aging, inflammation, immunity and periodontal disease (Q38921842)

7 September 2017

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title

Aging, inflammation, immunity and periodontal disease (English)

1 reference

7 September 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501491%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Hartsfield JK Jr

7

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Subramanya N M Pandruvada

12 June 2020

9

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12 June 2020

author name string

Jeffrey L Ebersole

1

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12 June 2020

Octavio A Gonzalez

3

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12 June 2020

Dolph Dawson

4

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12 June 2020

Lorri A Morford

5

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12 June 2020

Pinar Emecen Huja

6

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12 June 2020

Sarandeep S Huja

8

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12 June 2020

Shannon M Wallet

10

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12 June 2020

publication date

1 October 2016

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7 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501491%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

72

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12 June 2020

issue

1

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12 June 2020

page(s)

54-75

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Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway

12 June 2020

cites work

1 reference

Dendritic cells and aging: consequences for autoimmunity

21 January 2018

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Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA

21 January 2018

1 reference

The aging of early B-cell precursors

21 January 2018

1 reference

B cell development and receptor diversity during aging

21 January 2018

1 reference

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

21 January 2018

1 reference

Tumor necrosis factor-alpha gene -308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers

21 January 2018

1 reference

Ageing is associated with diminished apoptotic cell clearance in vivo

21 January 2018

1 reference

IL-4/CCL22/CCR4 axis controls regulatory T-cell migration that suppresses inflammatory bone loss in murine experimental periodontitis

21 January 2018

1 reference

Analysis of tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-10, IL-6, and interferon-gamma gene polymorphisms in patients with chronic periodontitis.

21 January 2018

1 reference

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

21 January 2018

1 reference

Natural killer cell function is altered during the primary response of aged mice to influenza infection.

21 January 2018

1 reference

Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?

21 January 2018

1 reference

Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery

21 January 2018

1 reference

Age effects on mouse and human B cells

21 January 2018

1 reference

Osteoclast differentiation and activation

21 January 2018

1 reference

Epigenetics of aging and aging-related disease.

21 January 2018

1 reference

Review article: ageing and the neutrophil: no appetite for killing?

21 January 2018

1 reference

Human natural killer cells

21 January 2018

1 reference

Influenza-induced production of interferon-alpha is defective in geriatric individuals

21 January 2018

1 reference

B cells and aging: molecules and mechanisms

21 January 2018

1 reference

Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor NKp46 aggravates periodontal disease

21 January 2018

1 reference

A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells

21 January 2018

1 reference

Effect of age on regulation of human osteoclast differentiation

21 January 2018

1 reference

Characterization of MHC-II antigen presentation by B cells and monocytes from older individuals

21 January 2018

1 reference

Autophagy and the immune function in aging

21 January 2018

1 reference

Aging and bone loss: new insights for the clinician

21 January 2018

1 reference

21 January 2018

1 reference

The effect of ageing on macrophage Toll-like receptor-mediated responses in the fight against pathogens

21 January 2018

1 reference

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells

21 January 2018

1 reference

Periodontal disease immunology: 'double indemnity' in protecting the host

21 January 2018

1 reference

Effects of age and oral disease on systemic inflammatory and immune parameters in nonhuman primates

21 January 2018

1 reference

Differential gender effects of a reduced-calorie diet on systemic inflammatory and immune parameters in nonhuman primates

21 January 2018

1 reference

The protective nature of host responses in periodontal diseases

21 January 2018

1 reference

Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty

21 January 2018

1 reference

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

21 January 2018

1 reference

Disorders of Bone Remodeling

21 January 2018

1 reference

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

21 January 2018

1 reference

Association of FOXO3A variation with human longevity confirmed in German centenarians

21 January 2018

1 reference

Aging and neutrophils: there is still much to do.

21 January 2018

1 reference

Epigenetic differences arise during the lifetime of monozygotic twins

21 January 2018

1 reference

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

21 January 2018

1 reference

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians

21 January 2018

1 reference

The network and the remodeling theories of aging: historical background and new perspectives

21 January 2018

1 reference

Aging Affects Human B Cell Responses

21 January 2018

1 reference

Age effects on B cells and humoral immunity in humans

21 January 2018

1 reference

Mechanisms for decreased function of B cells in aged mice and humans

21 January 2018

1 reference

Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans

21 January 2018

1 reference

Signal transduction and functional changes in neutrophils with aging.

21 January 2018

1 reference

A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17.

21 January 2018

1 reference

21 January 2018

1 reference

Pre-BCR signals and the control of Ig gene rearrangements

21 January 2018

1 reference

The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing

21 January 2018

1 reference

Innate immunity and aging

21 January 2018

1 reference

Comparative analysis of gingival tissue antigen presentation pathways in ageing and periodontitis

21 January 2018

1 reference

T cell development and receptor diversity during aging

21 January 2018

1 reference

Too old to fight? Aging and its toll on innate immunity

21 January 2018

1 reference

Periodontitis: from microbial immune subversion to systemic inflammation

21 January 2018

1 reference

Association of p53 codon 72 polymorphism and MDM2 SNP309 with clinical outcome of advanced nonsmall cell lung cancer

21 January 2018

1 reference

Disulfide Reduction in the Endocytic Pathway: Immunological Functions of Gamma-Interferon-Inducible Lysosomal Thiol Reductase

21 January 2018

1 reference

Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity.

21 January 2018

1 reference

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.

21 January 2018

1 reference

Effects of human aging on periodontal tissues.

21 January 2018

1 reference

Aging and epigenetic drift: a vicious cycle

21 January 2018

1 reference

In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease

21 January 2018

1 reference

Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

21 January 2018

1 reference

Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity

21 January 2018

1 reference

B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease

21 January 2018

1 reference

Association of longevity with IL-10 -1082 G/A and TNF-alpha-308 G/A polymorphisms

21 January 2018

1 reference

Dendritic cells stimulated with Actinobacillus actinomycetemcomitans elicit rapid gamma interferon responses by natural killer cells

21 January 2018

1 reference

TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin.

21 January 2018

1 reference

Is aging as complex as it would appear? New perspectives in aging research

21 January 2018

1 reference

The B‐cell biology of aging

21 January 2018

1 reference

Inflammatory mediators in the elderly

21 January 2018

1 reference

Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes

21 January 2018

1 reference

Effect of age on humoral immunity, selection of the B-cell repertoire and B-cell development.

21 January 2018

1 reference

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium

21 January 2018

1 reference

21 January 2018

1 reference

Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain

21 January 2018

1 reference

Conservation of pro-longevity genes among mammals.

21 January 2018

1 reference

Periodontal systemic associations: review of the evidence.

21 January 2018

1 reference

Ageing and the immune system: focus on macrophages

21 January 2018

1 reference

21 January 2018

1 reference

Allele frequencies of +874T-->A single nucleotide polymorphism at the first intron of interferon-gamma gene in a group of Italian centenarians

21 January 2018

1 reference

Gender-specific association between -1082 IL-10 promoter polymorphism and longevity

21 January 2018

1 reference

21 January 2018

The hallmarks of aging

1 reference

The role of osteopontin in inflammatory processes

21 January 2018

1 reference

Aging and the mucosal immune system in the intestine

21 January 2018

1 reference

Animal models for periodontal disease

21 January 2018

1 reference

The impact of ageing on the intestinal epithelial barrier and immune system.

21 January 2018

1 reference

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

21 January 2018

1 reference

A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects

21 January 2018

1 reference

The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

21 January 2018

1 reference

Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis

21 January 2018

1 reference

Proinflammatory cytokines, aging, and age-related diseases

21 January 2018

1 reference

The aging immune system: primer and prospectus

21 January 2018

1 reference

21 January 2018

1 reference

Aging mice exhibit a functional defect in mucosal dendritic cell response against an intracellular pathogen

21 January 2018

1 reference

The roles of cyclooxygenase-2 and prostaglandin E2 in periodontal disease

21 January 2018

1 reference

Impaired functions of peripheral blood monocyte subpopulations in aged humans

21 January 2018

1 reference

Systems Biology and immune aging

21 January 2018

1 reference

T-cell involvement in osteoclast biology: implications for rheumatoid bone erosion

21 January 2018

1 reference

TNF-alpha-308 G/A polymorphism and responsiveness to TNF-alpha blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis

21 January 2018

1 reference

Enumeration of human peripheral blood dendritic cells throughout the life

21 January 2018

1 reference

Animal Models for Periodontal Disease

21 January 2018

1 reference

Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response

21 January 2018

1 reference

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

21 January 2018

1 reference

Human immunosenescence: is it infectious?

21 January 2018

1 reference

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

21 January 2018

1 reference

Impaired in vivo CD4+ T cell expansion and differentiation in aged mice is not solely due to T cell defects: decreased stimulation by aged dendritic cells

21 January 2018

1 reference

21 January 2018

Periodontal diseases.

1 reference

Innate immunity in aging: impact on macrophage function

21 January 2018

1 reference

Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly

21 January 2018

1 reference

Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus

21 January 2018

1 reference

Tumour Necrosis Factor Gene Polymorphism and Disease Prevalence

21 January 2018

1 reference

Causes and Consequences of Age-Related Changes in DNA Methylation: A Role for ROS?

21 January 2018

1 reference

Homeostasis of lymphocytes and monocytes in frequent blood donors

21 January 2018

1 reference

Effects of caloric restriction on inflammatory periodontal disease

21 January 2018

1 reference

Impaired B lymphopoiesis in old age: a role for inflammatory B cells?

21 January 2018

1 reference

Non-human primates used in studies of periodontal disease pathogenesis: a review of the literature

21 January 2018

1 reference

Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults

21 January 2018

1 reference

Age-dependent dysregulation of innate immunity

21 January 2018

1 reference

Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity

21 January 2018

1 reference

Peripheral blood dendritic cells reinduce proliferation in in vitro aged T cell populations

21 January 2018

1 reference

Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes

21 January 2018

1 reference

Autophagy Controls Acquisition of Aging Features in Macrophages

21 January 2018

1 reference

Homeostasis and the age-associated defect of CD4 T cells

21 January 2018

1 reference

Osteoimmunology and the effects of the immune system on bone

21 January 2018

1 reference

Involvement of T-lymphocytes in periodontal disease and in direct and indirect induction of bone resorption

21 January 2018

1 reference

Senescent remodeling of the innate and adaptive immune system in the elderly men with prostate cancer.

21 January 2018

1 reference

Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection

21 January 2018

1 reference

Innate immune dysfunctions in aged mice facilitate the systemic dissemination of methicillin-resistant S. aureus

21 January 2018

1 reference

Expanding roles of neutrophils in aging hosts

21 January 2018

1 reference

Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer

21 January 2018

1 reference

The onset age of periodontal destruction

21 January 2018

1 reference

The Ssc protein of enteric bacteria has significant homology to the acyltransferase Lpxa of lipid A biosynthesis, and to three acetyltransferases

21 January 2018

1 reference

Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II.

21 January 2018

1 reference

The effect of age on the B-cell repertoire

21 January 2018

1 reference

Aging of the immune system: how much can the adaptive immune system adapt?

21 January 2018

1 reference

FOXO3A genotype is strongly associated with human longevity

21 January 2018

1 reference

Impact of aging on antigen presentation cell function of dendritic cells

21 January 2018

1 reference

IL-1 up-regulates osteopontin expression in experimental crescentic glomerulonephritis in the rat.

21 January 2018

1 reference

An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging

21 January 2018

1 reference

Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence.

21 January 2018

1 reference

CD4 T cell defects in the aged: causes, consequences and strategies to circumvent

21 January 2018

1 reference

21 January 2018

1 reference

A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity

21 January 2018

1 reference

The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model

21 January 2018

1 reference

GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals

21 January 2018

1 reference

Effects of aging on triggering receptor expressed on myeloid cells (TREM)-1-induced PMN functions

21 January 2018

1 reference

Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility

21 January 2018

1 reference

Interleukin-6 expression and gene polymorphism are associated with severity of periodontal disease in a sample of Brazilian individuals

21 January 2018

1 reference

The immune risk phenotype is associated with IL-6 in the terminal decline stage: Findings from the Swedish NONA immune longitudinal study of very late life functioning

21 January 2018

1 reference

Interferon-γ +874 Polymorphism in the First Intron of the Human Interferon-γ Gene and Kidney Allograft Outcome

21 January 2018

1 reference

NOD2/CARD15 and TNFA, But Not ILLB and ILLRN, are Associated With Crohnʼs Disease

21 January 2018

1 reference

Aging reduces the functionality of anti-pneumococcal antibodies and the killing of Streptococcus pneumoniae by neutrophil phagocytosis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/PRD.12135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27501491%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference