Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA. (Q38902059)

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English	Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA.	scientific article

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2 March 2020

Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA (English)

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2 March 2020

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2 March 2020

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2 March 2020

Mohammad Hossein Modarressi

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2 March 2020

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Marjan Yaghmaie

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2 March 2020

Mehrdad Asghari Estiar

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2 March 2020

Kamran Alimoghaddam

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2 March 2020

Ardeshir Ghavamzadeh

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2 March 2020

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11 March 2015

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2 March 2020

Molecular Neurobiology

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2 March 2020

53

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2 March 2020

3

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2 March 2020

1808-1823

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2 March 2020

Advances in the treatment of malignant gliomas

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21 January 2018

Neuroblastoma: biological insights into a clinical enigma

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21 January 2018

Aurora a and B overexpression and centrosome amplification in early estrogen-induced tumor foci in the Syrian hamster kidney: implications for chromosomal instability, aneuploidy, and neoplasia

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21 January 2018

The cellular geography of aurora kinases

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21 January 2018

Aurora B expression correlates with aggressive behaviour in glioblastoma multiforme

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21 January 2018

Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation

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https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Expression of Aurora kinases in human thyroid carcinoma cell lines and tissues.

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21 January 2018

A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

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21 January 2018

Aurora kinases as targets in drug-resistant neuroblastoma cells

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21 January 2018

Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma.

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21 January 2018

Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma.

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21 January 2018

The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Phase I study of the Aurora B kinase inhibitor barasertib (AZD1152) to assess the pharmacokinetics, metabolism and excretion in patients with acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Phase I study of barasertib (AZD1152), a selective inhibitor of Aurora B kinase, in patients with advanced solid tumors.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Simultaneous determination of AZD1152 (prodrug) and AZD1152-hydroxyquinazoline pyrazol anilide by reversed phase liquid chromatography

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

The selective Aurora B kinase inhibitor AZD1152 as a novel treatment for hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Enhancement of radiation response in p53-deficient cancer cells by the Aurora-B kinase inhibitor AZD1152.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Mutant p53: one name, many proteins

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

The in vitro micronucleus technique

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

1 reference

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21 January 2018

Molecular basis of drug resistance in aurora kinases

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Identification of genes that confer tumor cell resistance to the aurora B kinase inhibitor, AZD1152.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

The impact of p53 and p73 on aneuploidy and cancer

1 reference

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21 January 2018

Triggering p53 after cytokinesis failure

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Inhibiting the aurora B kinase potently suppresses repopulation during fractionated irradiation of human lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Aurora kinase B/C inhibition impairs malignant glioma growth in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Profiling of UV-induced ATM/ATR signaling pathways.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

Mitotic catastrophe: a mechanism for avoiding genomic instability.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

The cellular response to general and programmed DNA double strand breaks

1 reference

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21 January 2018

DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9139-9

21 January 2018

p73 suppresses polyploidy and aneuploidy in the absence of functional p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/25752998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the p53 Family in Stabilizing the Genome and Preventing Polyploidization

1 reference

https://pubmed.ncbi.nlm.nih.gov/25752998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25752998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25752998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25752998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-015-9139-9

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Europe PubMed Central

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2 March 2020

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2 March 2020

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