Anthraquinones As Pharmacological Tools and Drugs (Q38816745)

6 September 2017

title

Anthraquinones As Pharmacological Tools and Drugs (English)

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6 September 2017

2

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6 September 2017

Enas M Malik

1

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6 September 2017

publication date

25 April 2016

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Medicinal Research Reviews

6 September 2017

published in

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6 September 2017

volume

36

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6 September 2017

issue

4

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6 September 2017

page(s)

705-748

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Ueber Alizarin und Anthracen

6 September 2017

cites work

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Synthesis and anticancer structure activity relationship investigation of cationic anthraquinone analogs.

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Library synthesis and antibacterial investigation of cationic anthraquinone analogs.

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Anti-human cytomegalovirus activity and toxicity of sulfonated anthraquinones and anthraquinone derivatives

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Antiplatelet effect and selective binding to cyclooxygenase by molecular docking analysis of 3-alkylaminopropoxy-9,10-anthraquinone derivatives

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High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

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Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent

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Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS.

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A fruitful decade from 2005 to 2014 for anthraquinone patents

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Anthracycline and anthraquinone anticancer agents: current status and recent developments

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Adriamycin, 14-hydroxydaimomycin, a new antitumor antibiotic fromS. Peucetius var.caesius

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Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

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Limitations in doxorubicin production from Streptomyces peucetius

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Synthesis and antitumor properties of new glycosides of daunomycinone and adriamycinone

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Production of the antitumor drug epirubicin (4′-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius

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Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin

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Epirubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cancer chemotherapy

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Mechanism of action of mitoxantrone

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Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer

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Targeting DNA topoisomerase II in cancer chemotherapy

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Cellular roles of dna topoisomerases: a molecular perspective

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

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On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

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Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems.

21 January 2018

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Formation of genotoxic metabolites from anthraquinone glycosides, present in Rubia tinctorum L

21 January 2018

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Genotoxicity of naturally occurring hydroxyanthraquinones

21 January 2018

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In VitroReceptor Binding and Enzyme Inhibition byHypericum perforatumExtract

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Barbaloin: a concise report of its pharmacological and analytical aspects

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Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers--an in vitro model for intestinal absorption

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Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fibre combination.

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Chronic constipation: an evidence-based review

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Neuroprotective effects of emodin-8-O-beta-D-glucoside in vivo and in vitro

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Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities

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Adverse effects of laxatives: fact and fiction

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Is Chronic Use of Stimulant Laxatives Harmful to the Colon?

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Alterations in colonic anatomy induced by chronic stimulant laxatives: the cathartic colon revisited

21 January 2018

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Oral aloe vera-induced hepatitis

21 January 2018

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Acute hepatitis induced by an Aloe vera preparation: a case report

21 January 2018

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Aloe-induced toxic hepatitis

21 January 2018

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Appropriate use of laxatives in the management of constipation

21 January 2018

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Effects of diacerein at the molecular level in the osteoarthritis disease process

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Stimulating effect of diacerein on TGF-beta1 and beta2 expression in articular chondrocytes cultured with and without interleukin-1.

21 January 2018

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The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treatment period

21 January 2018

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Evaluation of the structure-modifying effects of diacerein in hip osteoarthritis: ECHODIAH, a three-year, placebo-controlled trial. Evaluation of the Chondromodulating Effect of Diacerein in OA of the Hip.

21 January 2018

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The interaction of anthraquinone dyes with the plasmid-mediated OXA-2 beta-lactamase

21 January 2018

1 reference

Inhibition of NAD(P)H:(quinone-acceptor) oxidoreductase by Cibacron Blue and related anthraquinone dyes: a structure-activity study

21 January 2018

1 reference

Interaction of Cibacron Blue 3G-A and related dyes with nucleotide-requiring enzymes

21 January 2018

1 reference

X-Ray Studies of the Binding of Cibacron Blue F3GA to Liver Alcohol Dehydrogenase

21 January 2018

1 reference

Purification and crystallization of rat liver NAD(P)H:(quinone-acceptor) oxidoreductase by cibacron blue affinity chromatography: identification of a new and potent inhibitor

21 January 2018

1 reference

Binding of Cibacron blue F3GA to proteins containing the dinucleotide fold

21 January 2018

1 reference

Constitutional isomers of Reactive Blue 2 - selective P2Y-receptor antagonists?

21 January 2018

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The gel-filtration behaviour of proteins related to their molecular weights over a wide range

21 January 2018

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Separation of Urinary Constituents of Low Molecular Weight on Sephadex G 10

21 January 2018

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Isolation of recombinant BMP receptor IA ectodomain and its 2:1 complex with BMP-2

21 January 2018

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Purification and characterization of hemagglutinating proteins from Poker-chip Venus (Meretrix lusoria) and Corbicula clam (Corbicula fluminea).

21 January 2018

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Protein-protein interactions as a strategy towards protein-specific drug design: the example of ataxin-1

21 January 2018

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A high molecular weight glycoprotein in seminal plasma is a sperm immobilizing factor in the teleost Nile tilapia, Oreochromis niloticus

21 January 2018

1 reference

Binding of HeLa CNA-polymerase alpha to blue dextran: a possible artefact in molecular weight determination by gel filtration

21 January 2018

1 reference

Reciprocity of yeast-phosphofructokinase with dextran blue 2000

21 January 2018

1 reference

Purine receptors in the guinea-pig internal anal sphincter

21 January 2018

1 reference

P2-purinoceptors of two subtypes in the rabbit mesenteric artery: reactive blue 2 selectively inhibits responses mediated via the P2y-but not the P2x-purinoceptor

21 January 2018

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Gastric motor responses elicited by vagal stimulation and purine compounds in the atropine-treated rabbit

21 January 2018

1 reference

An electrophysiological analysis of the effect of reactive blue 2, a putative P2-purinoceptor antagonist, on inhibitory junction potentials of rat caecum

21 January 2018

1 reference

Antagonism by reactive blue 2 but not by brilliant blue G of extracellular ATP-evoked responses in PC12 phaeochromocytoma cells

21 January 2018

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The P2Y purinoceptor in rat brain microvascular endothelial cells couple to inhibition of adenylate cyclase

21 January 2018

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Reactive blue 2 selectively inhibits P2y-purinoceptor-stimulated surfactant phospholipid secretion from rat isolated alveolar type II cells

21 January 2018

1 reference

Purinoceptors: are there families of P2X and P2Y purinoceptors?

21 January 2018

1 reference

Structure-activity relationships of novel P2-receptor antagonists structurally related to Reactive Blue 2.

21 January 2018

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P2-receptor antagonists: IV. Blockade of P2-receptor subtypes and ecto-nucleotidases by compounds related to reactive blue 2.

21 January 2018

1 reference

Purine and pyrimidine receptors

21 January 2018

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Medicinal chemistry of P2X receptors: allosteric modulators

21 January 2018

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Purine and pyrimidine (P2) receptors as drug targets

21 January 2018

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21 January 2018

P2 receptors and cancer

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Introduction: P2 receptors

21 January 2018

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Blue dextran-sepharose: an affinity column for the dinucleotide fold in proteins

21 January 2018

1 reference

Predicted distribution of NAD domain among glycolytic enzymes

21 January 2018

1 reference

Applications of blue dextran and Cibacron Blue F3GA in purification and structural studies of nucleotide-requiring enzymes

21 January 2018

1 reference

Dinucleotide fold proteins. Interaction of arabinose binding protein with Cibacron Blue 3G-A.

21 January 2018

1 reference

Inhibition of monkey liver serine hydroxymethyltransferase by Cibacron Blue 3G-A.

21 January 2018

1 reference

The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction

21 January 2018

1 reference

The specific interaction of Cibacron and related dyes with cyclic nucleotide phosphodiesterase and lactate dehydrogenase

21 January 2018

1 reference

Combinatorial synthesis of anilinoanthraquinone derivatives and evaluation as non-nucleotide-derived P2Y2 receptor antagonists

21 January 2018

1 reference

Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold

21 January 2018

1 reference

Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases).

21 January 2018

1 reference

Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071

21 January 2018

1 reference

High-throughput assays for promiscuous inhibitors.

21 January 2018

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Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures

21 January 2018

1 reference

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

21 January 2018

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Development of a virtual screening method for identification of "frequent hitters" in compound libraries

21 January 2018

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New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

21 January 2018

1 reference

ALARM NMR: a rapid and robust experimental method to detect reactive false positives in biochemical screens

21 January 2018

1 reference

Promiscuous aggregate-based inhibitors promote enzyme unfolding

21 January 2018

1 reference

Toxicological evaluation of thiol-reactive compounds identified using a la assay to detect reactive molecules by nuclear magnetic resonance

21 January 2018

1 reference

A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase

21 January 2018

1 reference

Multiparameter analysis of a screen for progesterone receptor ligands: comparing fluorescence lifetime and fluorescence polarization measurements

21 January 2018

1 reference

Kinase inhibitors: not just for kinases anymore

21 January 2018

1 reference

Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries

21 January 2018

1 reference

Cellular function and molecular structure of ecto-nucleotidases.

21 January 2018

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Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor

21 January 2018

1 reference

Convergent synthesis of the potent P2Y receptor antagonist MG 50-3-1 based on a regioselective Ullmann coupling reaction.

21 January 2018

1 reference

Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway

21 January 2018

1 reference

Mutagenicity of quinones: pathways of metabolic activation and detoxification

21 January 2018

1 reference

Molecular mechanisms of quinone cytotoxicity

21 January 2018

1 reference

Redox and addition chemistry of quinoid compounds and its biological implications

21 January 2018

1 reference

Synthesis and evaluation of quinonoid compounds against tumor cell lines

21 January 2018

1 reference

A review of the toxicity and carcinogenicity of anthraquinone derivatives

21 January 2018

1 reference

Free radical formation by antitumor quinones

21 January 2018

1 reference

Studies on quinones. Part 46. Synthesis and in vitro antitumor evaluation of aminopyrimidoisoquinolinequinones

21 January 2018

1 reference

Kinetics of redox interaction between substituted quinones and ascorbate under aerobic conditions.

21 January 2018

1 reference

Computation of the redox and protonation properties of quinones: towards the prediction of redox cycling natural products

21 January 2018

1 reference

The reaction of menadione with haemoglobin. Mechanism and effect of superoxide dismutase

21 January 2018

1 reference

Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs

21 January 2018

1 reference

Redox chemistry of anthracycline antitumor drugs and use of captodative radicals as tools for its elucidation and control

21 January 2018

1 reference

Prevention of anthracycline-induced cardiotoxicity: challenges and opportunities

21 January 2018

1 reference

Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase: implications for increasing the activity against sensitive and multidrug-resistant

21 January 2018

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Studies on the mechanism of action of quinone antitumor agents

21 January 2018

1 reference

Adriamycin dose and time effects on cell cycle, cell death, and reactive oxygen species generation in leukaemia cells.

21 January 2018

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Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity

21 January 2018

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Dexrazoxane (Totect): FDA review and approval for the treatment of accidental extravasation following intravenous anthracycline chemotherapy

21 January 2018

1 reference

Mechanisms and management of doxorubicin cardiotoxicity

21 January 2018

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Identification of the molecular basis of doxorubicin-induced cardiotoxicity

21 January 2018

1 reference

Mutagenesis by 9,10-anthraquinone derivatives and related compounds in Salmonella typhimurium

21 January 2018

1 reference

Mutagenicity of anthraquinone and benzanthrone derivatives in the salmonella/microsome test: Activation of anthraquinone glycosides by enzymic extracts of rat cecal bacteria

21 January 2018

1 reference

A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds

21 January 2018

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Characterization of the genotoxicity of anthraquinones in mammalian cells

21 January 2018

1 reference

The Ames Salmonella/microsome mutagenicity assay

21 January 2018

1 reference

The alkaline comet assay: towards validation in biomonitoring of DNA damaging exposures

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay.

21 January 2018

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Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors

21 January 2018

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Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model

21 January 2018

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Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis

21 January 2018

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The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines

21 January 2018

1 reference

Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation

21 January 2018

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Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells.

21 January 2018

1 reference

Factors influencing constipation in advanced cancer patients: a prospective study of opioid dose, dantron dose and physical functioning

21 January 2018

1 reference

Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test

21 January 2018

1 reference

Genotoxicological assessment of two reactive dyes extracted from cotton fibres using artificial sweat.

21 January 2018

1 reference

Human sulfotransferases and their role in chemical metabolism.

21 January 2018

1 reference

A safe strategy for addition of vitamins and minerals to foods.

21 January 2018

1 reference

Biochemical, physiological and medical aspects of ubiquinone function

21 January 2018

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Distribution and redox state of ubiquinones in rat and human tissues

21 January 2018

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Enzymic and non-enzymic antioxidants in epidermis and dermis of human skin

21 January 2018

1 reference

Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects

21 January 2018

1 reference

Ullmann reactions of 1-amino-4-bromoanthraquinones bearing various 2-substituents furnishing novel dyes

21 January 2018

1 reference

Rapid and Efficient Microwave-Assisted Copper(0)-Catalyzed Ullmann Coupling Reaction: General Access to Anilinoanthraquinone Derivatives

21 January 2018

1 reference

Purification, properties, and characterization of recombinant Streptomyces sp. strain C5 DoxA, a cytochrome P-450 catalyzing multiple steps in doxorubicin biosynthesis

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.181.1.298-304.1999

Identifiers

DOI

10.1002/MED.21391

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6 September 2017

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