Increasing role of the cancer chemotherapeutic doxorubicin in cellular metabolism (Q38779463)

6 September 2017

title

Increasing role of the cancer chemotherapeutic doxorubicin in cellular metabolism (English)

1 reference

6 September 2017

1 reference

1 reference

Ann-Marie Meredith

1

1 reference

6 September 2017

Crispin R Dass

series ordinal

2

1 reference

6 September 2017

publication date

14 March 2016

1 reference

Journal of Pharmacy and Pharmacology

6 September 2017

published in

1 reference

6 September 2017

volume

68

1 reference

6 September 2017

issue

6

1 reference

6 September 2017

page(s)

729-741

1 reference

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

6 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Myocet (liposome-encapsulated doxorubicin citrate): a new approach in breast cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Hodgkin's disease in the elderly: improved treatment outcome with a doxorubicin-containing regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin: the good, the bad and the ugly effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

The inhibition in vitro of DNA polymerase and RNA polymerases by daunomycin and adriamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Probing the dynamics of doxorubicin-DNA intercalation during the initial activation of apoptosis by fluorescence lifetime imaging microscopy (FLIM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and biological review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

DNA and its associated processes as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Growth state and cell cycle dependent phosphorylation of DNA topoisomerase II in Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Reduced activity of topoisomerase II in an Adriamycin-resistant human stomach-adenocarcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Apoptosis, autophagy, and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Death by design: apoptosis, necrosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

When apoptosis meets autophagy: deciding cell fate after trauma and sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Activation of AMP-activated protein kinase contributes to doxorubicin-induced cell death and apoptosis in cultured myocardial H9c2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Promotion of autophagy and inhibition of apoptosis by low concentrations of cadmium in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Autophagy regulates the processing of amino terminal huntingtin fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Autophagy in disease: a double-edged sword with therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Autophagy in DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Insulin-like growth factor-1 and TNF-alpha regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Caspase inhibition switches doxorubicin-induced apoptosis to senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Alkylating DNA damage stimulates a regulated form of necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Programmed necrosis and necroptosis signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Role of mtDNA lesions in anthracycline cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Intracellular accumulation and mechanism of action of doxorubicin in a spatio-temporal tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Heterogeneity of mitochondria and mitochondrial function within cells as another level of mitochondrial complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Mitochondria: more than just a powerhouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Mitochondria: dynamic organelles in disease, aging, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Mitochondrial form and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Exercise as a beneficial adjunct therapy during Doxorubicin treatment--role of mitochondria in cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Mitochondria-derived reactive oxygen species play an important role in Doxorubicin-induced platelet apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Doxorubicin-induced in vivo nephrotoxicity involves oxidative stress-mediated multiple pro- and anti-apoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12539

21 January 2018

Identifiers

DOI

10.1111/JPHP.12539

1 reference

6 September 2017

1 reference