Impact of IgG Fc-Oligosaccharides on Recombinant Monoclonal Antibody Structure, Stability, Safety, and Efficacy. (Q38762019)

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21 March 2020

review article

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title

Impact of IgG Fc-Oligosaccharides on Recombinant Monoclonal Antibody Structure, Stability, Safety, and Efficacy (English)

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21 March 2020

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21 March 2020

author name string

Christine Nowak

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21 March 2020

Bruce Andrien

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21 March 2020

Mei Shao

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21 March 2020

Gomathinayagam Ponniah

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21 March 2020

Alyssa Neill

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publication date

12 June 2017

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21 March 2020

published in

Biotechnology Progress

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21 March 2020

volume

33

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issue

5

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21 March 2020

page(s)

1173-1181

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Glycosylation in the Fc domain of IgG increases resistance to proteolytic cleavage by papain.

21 March 2020

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The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

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Identifiers

DOI

10.1002/BTPR.2498

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28547754%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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