Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. (Q38717899)

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1 April 2020

title

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras (English)

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7

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Timothy C Wang

1

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David M. Sabatini

9

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8

Eric S Lander

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author name string

Haiyan Yu

2

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Nicholas W Hughes

3

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Bingxu Liu

4

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Arek Kendirli

5

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Klara Klein

6

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language of work or name

English

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publication date

2 February 2017

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1 April 2020

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volume

168

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issue

5

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page(s)

890-903.e15

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A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

1 April 2020

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

23 June 2018

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K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

23 June 2018

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23 June 2018

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Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.

23 June 2018

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CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions

31 August 2018

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Genetic Interactions in Cancer Progression and Treatment

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28162770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2017.01.013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28162770%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28162770%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

28162770

1 reference