Structural determinants of Smad function in TGF-β signaling. (Q38454947)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

review article

1 reference

title

Structural determinants of Smad function in TGF-β signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Pau Martín-Malpartida

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Joan Massagué Solé

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

author name string

Maria J Macias

1

1 reference

3 September 2017

Pau Martin-Malpartida

2

1 reference

3 September 2017

Joan Massagué

3

1 reference

3 September 2017

29 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

Trends in Biochemical Sciences

7 March 2020

number of pages

13

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

40

1 reference

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7 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

296-308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.

7 March 2020

cites work

1 reference

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Deciphering the genetic programme triggering timely and spatially-regulated chitin deposition

6 September 2017

1 reference

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The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-β signaling

6 September 2017

1 reference

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COSMIC: exploring the world's knowledge of somatic mutations in human cancer

6 September 2017

1 reference

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The biology of YAP/TAZ: hippo signaling and beyond

6 September 2017

1 reference

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Sensing the local environment: actin architecture and Hippo signalling

6 September 2017

1 reference

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The novel Smad protein Expansion regulates the receptor tyrosine kinase pathway to control Drosophila tracheal tube size

6 September 2017

1 reference

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6 September 2017

1 reference

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The analysis of eight transcriptomes from all poriferan classes reveals surprising genetic complexity in sponges

6 September 2017

1 reference

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Emerging patterns of somatic mutations in cancer

6 September 2017

1 reference

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The harmonies played by TGF-β in stem cell biology

6 September 2017

1 reference

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TGFβ signalling in context

6 September 2017

1 reference

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Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Evolution of the TGF-β signaling pathway and its potential role in the ctenophore, Mnemiopsis leidyi

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Structural basis for the cooperative DNA recognition by Smad4 MH1 dimers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors

6 September 2017

1 reference

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The Hippo Signaling Pathway in Development and Cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Regulation of TGF-beta signalling by protein phosphatases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

The Amphimedon queenslandica genome and the evolution of animal complexity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Signaling by members of the TGF-beta family in vascular morphogenesis and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

The polarization of immune cells in the tumour environment by TGFbeta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

TGFbeta signalling: a complex web in cancer progression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF- effectors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

The dawn of developmental signaling in the metazoa

6 September 2017

1 reference

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Improved prediction of protein side-chain conformations with SCWRL4

6 September 2017

1 reference

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Tgf-beta superfamily signaling in embryonic development and homeostasis

6 September 2017

1 reference

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Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

6 September 2017

1 reference

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Emergence, development and diversification of the TGF-beta signalling pathway within the animal kingdom

6 September 2017

1 reference

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Regulation of TGF-beta family signaling by E3 ubiquitin ligases

6 September 2017

1 reference

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The Trichoplax genome and the nature of placozoans

6 September 2017

1 reference

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6 September 2017

1 reference

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Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

6 September 2017

1 reference

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Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.

6 September 2017

1 reference

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Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling

6 September 2017

1 reference

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An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2

6 September 2017

1 reference

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Smad transcription factors

6 September 2017

1 reference

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Non-Smad TGF-beta signals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Structural basis of heteromeric smad protein assembly in TGF-beta signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

6 September 2017

1 reference

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X-ray crystal structure of IRF-3 and its functional implications

6 September 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

6 September 2017

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

6 September 2017

1 reference

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Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control

6 September 2017

1 reference

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WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

6 September 2017

1 reference

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Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling

6 September 2017

1 reference

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Mh1 domain of Smad is a degraded homing endonuclease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Structural basis of Smad2 recognition by the Smad anchor for receptor activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

6 September 2017

1 reference

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SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

6 September 2017

1 reference

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TGF-beta signal transduction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Human Smad3 and Smad4 are sequence-specific transcription activators

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

A structural basis for mutational inactivation of the tumour suppressor Smad4

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Mechanism of activation of the TGF-beta receptor

6 September 2017

1 reference

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Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4.

6 September 2017

1 reference

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Endofin acts as a Smad anchor for receptor activation in BMP signaling

6 September 2017

1 reference

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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

23 June 2018

1 reference

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485443

Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells.

23 June 2018

1 reference

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Cancer genomics: A panoramic view of cancer

31 August 2018

1 reference

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TGF-β signaling in development and disease

31 August 2018

1 reference

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Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development

31 August 2018

1 reference

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TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.

31 August 2018

1 reference

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Homozygous deletion map at 18q21.1 in pancreatic cancer

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25935112

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TIBS.2015.03.012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25935112%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

25935112

1 reference