Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin (Q38358692)

2 September 2017

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin (English)

1 reference

2 September 2017

Emanuel Rognoni

4

0 references

Reinhard Fässler

11

object named as

Reinhard Fässler

1 reference

2 September 2017

Marina Theodosiou

1

1 reference

2 September 2017

Moritz Widmaier

2

1 reference

2 September 2017

Ralph T Böttcher

3

1 reference

2 September 2017

Maik Veelders

5

1 reference

2 September 2017

Mitasha Bharadwaj

6

1 reference

2 September 2017

Armin Lambacher

7

1 reference

2 September 2017

Katharina Austen

8

1 reference

2 September 2017

Daniel J Müller

9

1 reference

2 September 2017

Roy Zent

10

1 reference

2 September 2017

language of work or name

English

0 references

publication date

27 January 2016

1 reference

2 September 2017

1 reference

2 September 2017

5

1 reference

2 September 2017

e10130

1 reference

describes a project that uses

2 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4749545/fullTextXML

inferred from PubMed Central ID database lookup

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6 September 2017

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Diverse roles for the paxillin family of proteins in cancer

6 September 2017

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FAK promotes recruitment of talin to nascent adhesions to control cell motility

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects

6 September 2017

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6 September 2017

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Talin depletion reveals independence of initial cell spreading from integrin activation and traction

6 September 2017

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Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

6 September 2017

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Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction

6 September 2017

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Kindlin-2 controls bidirectional signaling of integrins

6 September 2017

1 reference

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Kindlin-3 is essential for integrin activation and platelet aggregation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

6 September 2017

1 reference

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The Kindlins: subcellular localization and expression during murine development

6 September 2017

1 reference

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Structure and function of the platelet integrin alphaIIbbeta3

6 September 2017

1 reference

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Control of motile and invasive cell phenotypes by focal adhesion kinase.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Integrins: bidirectional, allosteric signaling machines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Avidity regulation of integrins: the driving force in leukocyte adhesion

6 September 2017

1 reference

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Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha(5)beta(1) integrins promotes early fibronectin fibrillogenesis

6 September 2017

1 reference

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Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Consequences of lack of beta 1 integrin gene expression in mice

6 September 2017

1 reference

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Cyclic mechanical reinforcement of integrin-ligand interactions

6 September 2017

1 reference

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The RGD motif in fibronectin is essential for development but dispensable for fibril assembly

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Automated tool for the detection of cell nuclei in digital microscopic images: application to retinal images.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Cell adhesion and motility depend on nanoscale RGD clustering.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

27 September 2017

1 reference

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Trimers of the fibronectin cell adhesion domain localize to actin filament bundles and undergo rearward translocation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor.

31 August 2018

1 reference

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Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Regulation of the fibronectin receptor affinity by divalent cations.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749545

Calibration of atomic‐force microscope tips

31 August 2018

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Crossref

https://api.crossref.org/works/10.7554%2FELIFE.10130

Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.10130

Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.10130

Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26821125

12 December 2020

inferred from PubMed ID database lookup

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26821125

12 December 2020

inferred from PubMed ID database lookup

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26821125

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.7554/ELIFE.10130

1 reference

2 September 2017

1 reference

2 September 2017

PubMed publication ID

26821125

1 reference