The role of Hfe in transferrin-bound iron uptake by hepatocytes (Q38292010)

1 September 2017

title

The role of Hfe in transferrin-bound iron uptake by hepatocytes (English)

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1 September 2017

5

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1 September 2017

Anita C G Chua

1

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1 September 2017

Carly E Herbison

2

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1 September 2017

Sarah F Drake

3

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1 September 2017

Ross M Graham

4

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1 September 2017

Debbie Trinder

6

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1 September 2017

language of work or name

English

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publication date

1 May 2008

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1 September 2017

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1 September 2017

volume

47

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1 September 2017

issue

5

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1 September 2017

page(s)

1737-1744

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HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface

1 September 2017

cites work

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Transferrin receptor 2 mediates uptake of transferrin-bound and non-transferrin-bound iron

21 January 2018

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Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE

21 January 2018

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Diferric transferrin regulates transferrin receptor 2 protein stability

21 January 2018

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Regulation of transferrin receptor 2 protein levels by transferrin

21 January 2018

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Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies

21 January 2018

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Recycling, degradation and sensitivity to the synergistic anion of transferrin in the receptor-independent route of iron uptake by human hepatoma (HuH-7) cells

21 January 2018

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The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

21 January 2018

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Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis

21 January 2018

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Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

21 January 2018

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Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

21 January 2018

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A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

21 January 2018

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Mechanisms of disease: The role of hepcidin in iron homeostasis--implications for hemochromatosis and other disorders

21 January 2018

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Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.

21 January 2018

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Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

21 January 2018

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Hepcidin is decreased in TFR2 hemochromatosis

21 January 2018

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Localization of iron metabolism–related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes

21 January 2018

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Limited iron export by hepatocytes contributes to hepatic iron-loading in the Hfe knockout mouse.

21 January 2018

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Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

21 January 2018

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IN VIVO BEHAVIOR OF I-FIBRINOGEN.

21 January 2018

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Lack of hepatic transferrin receptor expression in hemochromatosis

21 January 2018

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Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

21 January 2018

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The uptake of iron and transferrin by the human malignant melanoma cell

21 January 2018

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Two saturable mechanisms of iron uptake from transferrin in human melanoma cells: the effect of transferrin concentration, chelators, and metabolic probes on transferrin and iron uptake

21 January 2018

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Activation of an iron uptake mechanism from transferrin in hepatocytes by small-molecular-weight iron complexes: implications for the pathogenesis of iron-overload disease

21 January 2018

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Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

21 January 2018

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The effects of an antibody to the rat transferrin receptor and of rat serum albumin on the uptake of diferric transferrin by rat hepatocytes

21 January 2018

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7 January 2021

Decreased liver hepcidin expression in the Hfe knockout mouse

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7 January 2021

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3

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7 January 2021

A comparative study of chemically and enzymatically radioiodinated transferrin

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7 January 2021

Effects of cell proliferation on the uptake of transferrin-bound iron by human hepatoma cells

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7 January 2021

Intracellular processing of transferrin and iron by isolated rat hepatocytes

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7 January 2021

The mechanisms of iron uptake by fetal rat hepatocytes in culture

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7 January 2021

Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis

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7 January 2021

Identifiers

DOI

10.1002/HEP.22180

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1 September 2017

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