Small heat-shock proteins: important players in regulating cellular proteostasis (Q38263437)

1 September 2017

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title

Small heat-shock proteins: important players in regulating cellular proteostasis (English)

1 reference

1 September 2017

Heath Ecroyd

3

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John Carver

object named as

John A Carver

series ordinal

4

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Teresa M Treweek

series ordinal

1

object named as

Teresa M Treweek

1 reference

1 September 2017

2

Sarah Meehan

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1 September 2017

publication date

29 October 2014

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Cellular and Molecular Life Sciences

1 September 2017

published in

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1 September 2017

volume

72

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1 September 2017

issue

3

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1 September 2017

page(s)

429-451

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Metastability of Native Proteins and the Phenomenon of Amyloid Formation

1 September 2017

cites work

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Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins

21 January 2018

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Small heat-shock proteins: paramedics of the cell

21 January 2018

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Small heat shock proteins and protein-misfolding diseases

21 January 2018

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Large potentials of small heat shock proteins

21 January 2018

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Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

21 January 2018

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Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Extracellular chaperones and proteostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

One size does not fit all: the oligomeric states of αB crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The small heat-shock protein, alphaB-crystallin, has a variable quaternary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Subunit Exchange of αA-Crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

NMR spectroscopy of alpha-crystallin. Insights into the structure, interactions and chaperone action of small heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Probing the structure and interactions of crystallin proteins by NMR spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Selective NMR Experiments on Macromolecules: Implementation and Analysis of QUIET-NOESY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Crystal structure of a small heat-shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Crystal structure and assembly of a eukaryotic small heat shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The structured core domain of B-crystallin can prevent amyloid fibrillation and associated toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

N-terminal domain of B-crystallin provides a conformational switch for multimerization and structural heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Dynamical structure of αB-crystallin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat-shock protein structures reveal a continuum from symmetric to variable assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Lens alpha-crystallin: function and structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The eye lens chaperone alpha-crystallin forms defined globular assemblies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Crystallin proteins and amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Structural changes in alpha-crystallin and whole eye lens during heating, observed by low-angle X-ray diffraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha-crystallin can function as a molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Lens crystallins: the evolution and expression of proteins for a highly specialized tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Lens organelle degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

On the mechanism of organelle degradation in the vertebrate lens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Lens differentiation in vertebrates. A review of cellular and molecular features

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

alpha-Crystallin quaternary structure and interactive properties control eye lens transparency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

On the growth and internal structure of the human lens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Amyloid-like protein structure in mammalian ocular lenses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

The vertebrate eye lens

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The function of alpha-crystallin in vision

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A transgenic mouse model for human autosomal dominant cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Intermolecular Exchange and Stabilization of Recombinant Human αA- and αB-Crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

alphaB-crystallin exists as an independent protein in the heart and in the lens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha B-crystallin is expressed in kidney epithelial cell lines and not in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha B-crystallin in the mammalian inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat shock proteins HSP27 and alphaB-crystallin: cytoprotective and oncogenic functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Hypertonic stress induces alpha B-crystallin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha-crystallin as a molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha B-crystallin is a small heat shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha A-crystallin confers cellular thermoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The distinctive role of small heat shock proteins in oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat shock proteins in cancer therapy and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Pathological changes in levels of three small stress proteins, alphaB crystallin, HSP 27 and p20, in the hindlimb muscles of dy mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Analysis of the dominant effects mediated by wild type or R120G mutant of αB-crystallin (HspB5) towards Hsp27 (HspB1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Subunit exchange of small heat shock proteins. Analysis of oligomer formation of alphaA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Heterooligomeric complexes formed by human small heat shock proteins HspB1 (Hsp27) and HspB6 (Hsp20).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Structural and functional aspects of hetero-oligomers formed by the small heat shock proteins αB-crystallin and HSP27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The small heat-shock proteins HSPB2 and HSPB3 form well-defined heterooligomers in a unique 3 to 1 subunit ratio.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Utilization of fluorescent chimeras for investigation of heterooligomeric complexes formed by human small heat shock proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Expression, purification and some properties of fluorescent chimeras of human small heat shock proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phorbol ester-induced generation of reactive oxygen species is protein kinase cbeta -dependent and required for SAPK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha-crystallin-type heat shock proteins: socializing minichaperones in the context of a multichaperone network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The interaction of the molecular chaperone, alpha-crystallin, with molten globule states of bovine alpha-lactalbumin

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

12 December 2020

The molecular chaperone, alpha-crystallin, inhibits amyloid formation by apolipoprotein C-II.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The molecular chaperone alpha-crystallin is in kinetic competition with aggregation to stabilize a monomeric molten-globule form of alpha-lactalbumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Evidence for an essential function of the N terminus of a small heat shock protein in vivo, independent of in vitro chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Analysis of the regulation of the molecular chaperone Hsp26 by temperature-induced dissociation: the N-terminal domail is important for oligomer assembly and the binding of unfolding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The N-terminal domain of alphaB-crystallin is protected from proteolysis by bound substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Regulated structural transitions unleash the chaperone activity of αB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Mini-alphaB-crystallin: a functional element of alphaB-crystallin with chaperone-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Functional Elements in Molecular Chaperone α-Crystallin: Identification of Binding Sites in αB-Crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A novel quaternary structure of the dimeric alpha-crystallin domain with chaperone-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Mechanism of chaperone function in small heat-shock proteins. Phosphorylation-induced activation of two-mode binding in alphaB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha B crystallin and HSP28 are enhanced in the cerebral cortex of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Expression of alpha B-crystallin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Monitoring the prevention of amyloid fibril formation by alpha-crystallin. Temperature dependence and the nature of the aggregating species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

An analytical solution to the kinetics of breakable filament assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Dissociation is not required for alpha-crystallin's chaperone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

AlphaB-crystallin in the rat lens is phosphorylated at an early post-natal age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Loss of the C-terminal serine residue from bovine beta B2-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Presbyopia and cataract: a question of heat and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Age-dependent deamidation of lifelong proteins in the human lens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Lens β-crystallins: the role of deamidation and related modifications in aging and cataract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Diabetic cataract formation: potential role of glycosylation of lens crystallins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation of HSP27 during development and decay of thermotolerance in Chinese hamster cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation of αB-Crystallin in Response to Various Types of Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation of alphaB-crystallin and HSP27 is induced by similar stressors in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The in vivo phosphorylation sites of bovine alpha B-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Identification of the posttranslational modifications of bovine lens αB‐crystallins by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

PKA phosphorylation of the small heat-shock protein Hsp20 enhances its cardioprotective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat-shock protein Hsp20 phosphorylation inhibits beta-agonist-induced cardiac apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation by cyclic AMP-dependent protein kinase inhibits chaperone-like activity of human HSP22 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Effect of phosphorylation on alpha B-crystallin: differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Essential role of the NH2-terminal WD/EPF motif in the phosphorylation-activated protective function of mammalian Hsp27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Nuclear speckle localisation of the small heat shock protein alpha B-crystallin and its inhibition by the R120G cardiomyopathy-linked mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Heat stress-induced localization of small heat shock proteins in mouse myoblasts: intranuclear lamin A/C speckles as target for alphaB-crystallin and Hsp25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat shock protein activity is regulated by variable oligomeric substructure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Phosphorylation-induced change of the oligomerization state of alpha B-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Serine 59 phosphorylation of {alpha}B-crystallin down-regulates its anti-apoptotic function by binding and sequestering Bcl-2 in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Multiple molecular architectures of the eye lens chaperone B-crystallin elucidated by a triple hybrid approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat-shock proteins and their potential role in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Defective protein folding as a basis of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The small heat shock proteins and their role in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

12 December 2020

Actin cytoskeleton and small heat shock proteins: how do they interact?

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

GFAP and its role in Alexander disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Vesicle associated membrane protein B (VAPB) is decreased in ALS spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alexander's disease in a Bernese mountain dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha-B-crystallin in neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The C-terminus of the beta protein is critical in amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Increased beta-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

αB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Recent progress in understanding Alzheimer's β-amyloid structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The importance of tau phosphorylation for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Expression of the small heat-shock protein alphaB-crystallin in tauopathies with glial pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Bovine PrPC directly interacts with alphaB-crystalline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The small heat shock proteins αB-crystallin and Hsp27 suppress SOD1 aggregation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Familial parkinsonism and dementia with ballooned neurons, argyrophilic neuronal inclusions, atypical neurofibrillary tangles, tau-negative astrocytic fibrillary tangles, and Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Chaperone Activity of α B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha-crystallins and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Serine phosphorylation and suppression of apoptosis by the small heat shock protein alphaB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Inhibition of Daxx-mediated apoptosis by heat shock protein 27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Stress-response proteins in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A novel mutation in AlphaA-crystallin (CRYAA) caused autosomal dominant congenital cataract in a large Chinese family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Abnormal small heat shock protein interactions involving neuropathy-associated HSP22 (HSPB8) mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

A novel Lys141Thr mutation in small heat shock protein 22 (HSPB8) gene in Charcot-Marie-Tooth disease type 2L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Alpha B-crystallin mutation in dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Infantile muscular dystrophy in Canadian aboriginals is an αB-crystallinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Genealogy of the alpha-crystallin--small heat-shock protein superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Cataract mutation P20S of alphaB-crystallin impairs chaperone activity of alphaA-crystallin and induces apoptosis of human lens epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Genetic heterogeneity in microcornea-cataract: five novel mutations in CRYAA, CRYGD, and GJA8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the alpha A crystallin gene (CRYAA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Interactive domains for chaperone activity in the small heat shock protein, human alphaB crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Temperature dependence of chaperone-like activity and oligomeric state of αB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Short-range order of crystallin proteins accounts for eye lens transparency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

αB-Crystallin mutation in dilated cardiomyopathies: Low prevalence in a consecutive series of 200 unrelated probands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

sHSPs under temperature and pressure: The opposite behaviour of lens alpha-crystallins and yeast HSP26

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1754-5

Structural and functional consequences of the mutation of a conserved arginine residue in alphaA and alphaB crystallins

21 January 2018

1 reference

12 December 2020

Mechanism of chaperone function in small heat shock proteins: dissociation of the HSP27 oligomer is required for recognition and binding of destabilized T4 lysozyme

1 reference

12 December 2020

Identification of the phosphorylation sites of the murine small heat shock protein hsp25

1 reference

12 December 2020

Physiological and pathological changes in levels of the two small stress proteins, HSP27 and alpha B crystallin, in rat hindlimb muscles

1 reference

12 December 2020

Post-translational modification of alphaB-crystallin of normal human lens

1 reference

12 December 2020

Rosenthal fibers share epitopes with alpha B-crystallin, glial fibrillary acidic protein, and ubiquitin, but not with vimentin. Immunoelectron microscopy with colloidal gold

1 reference

12 December 2020

Does post-translational modification influence chaperone-like activity of alpha-crystallin? I. Study on phosphorylation

1 reference

12 December 2020

The interaction of unfolding α-lactalbumin and malate dehydrogenase with the molecular chaperone αB-crystallin: a light and X-ray scattering investigation

1 reference

12 December 2020

Alpha-crystallin can act as a chaperone under conditions of oxidative stress

1 reference

12 December 2020

Mutation of R116C results in highly oligomerized alpha A-crystallin with modified structure and defective chaperone-like function

1 reference

12 December 2020

Characterization of a new, dominant V124E mutation in the mouse alphaA-crystallin-encoding gene

1 reference

12 December 2020

Evolution of the alpha-crystallin/small heat-shock protein family

1 reference

12 December 2020

A possible chaperone-like quaternary structure for alpha-crystallin

1 reference

12 December 2020

Chaperone-like activity and quaternary structure of alpha-crystallin

1 reference

12 December 2020

Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions

1 reference

12 December 2020

Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock

1 reference

12 December 2020

The microscopic protein structure of the lens with a theory for cataract formation as determined by Raman spectroscopy of intact bovine lenses

1 reference

12 December 2020

Overexpression and abnormal modification of the stress proteins alpha B-crystallin and HSP27 in Alexander disease

1 reference

12 December 2020

Small stress proteins: chaperones that act as regulators of intracellular redox state and programmed cell death

1 reference

12 December 2020

X-ray- and neutron-scattering studies of alpha-crystallin and evidence that the target protein sits in the fenestrations of the alpha-crystallin shell

1 reference

12 December 2020

Preventing α-synuclein aggregation: the role of the small heat-shock molecular chaperone proteins

1 reference

12 December 2020

Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin.

1 reference

12 December 2020

Subunit exchange of polydisperse proteins: mass spectrometry reveals consequences of alphaA-crystallin truncation

1 reference

12 December 2020

Packing-induced conformational and functional changes in the subunits of alpha -crystallin

1 reference

12 December 2020

Normal human lens - the distribution of protein

1 reference

12 December 2020

Investigation of gammaE-crystallin target protein binding to bovine lens alpha-crystallin by small-angle neutron scattering

1 reference

12 December 2020

A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation

1 reference

12 December 2020

Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle

1 reference

12 December 2020

The small heat shock-related protein, HSP20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation

1 reference

12 December 2020

Site-directed mutations in the C-terminal extension of human alphaB-crystallin affect chaperone function and block amyloid fibril formation

1 reference

12 December 2020

Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27.

1 reference

12 December 2020

Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils

1 reference

12 December 2020

Relocalization of alpha B-crystallin by heat shock in ovarian carcinoma cells

1 reference

12 December 2020

The small heat-shock protein αB-crystallin uses different mechanisms of chaperone action to prevent the amorphous versus fibrillar aggregation of α-lactalbumin

1 reference

12 December 2020

Purification of the stress protein αB-crystallin and its differentially phosphorylated forms

1 reference

12 December 2020

Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy

1 reference

12 December 2020

AlphaB-crystallin in lacrimal gland duct and tears

1 reference

12 December 2020

A nonsense mutation (W9X) in CRYAA causes autosomal recessive cataract in an inbred Jewish Persian family

1 reference

12 December 2020

hsp27 as a Switch between Differentiation and Apoptosis in Murine Embryonic Stem Cells

1 reference

12 December 2020

Ubiquitinated alpha B-crystallin in glial cytoplasmic inclusions from the brain of a patient with multiple system atrophy

1 reference

12 December 2020

Ultrastructural and immunohistochemical studies on ballooned cortical neurons in Creutzfeldt-Jakob disease: expression of alpha B-crystallin, ubiquitin and stress-response protein 27

1 reference

12 December 2020

Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase 2 is not essential for chaperone properties and cellular thermoresistance

1 reference

12 December 2020

Synthesis and characterization of a peptide identified as a functional element in alphaA-crystallin

1 reference

12 December 2020

Effect of cross-linking on the chaperone-like function of alpha crystallin

1 reference

12 December 2020

Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells. Relationship to the breakdown of abnormal proteins

1 reference

12 December 2020

R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable

1 reference

12 December 2020

alpha A-crystallin is expressed in non-ocular tissues

1 reference

12 December 2020

An examination of alpha B-crystallin as a modifier of SOD1 aggregate pathology and toxicity in models of familial amyotrophic lateral sclerosis.

1 reference

12 December 2020

Identification of a novel CRYAB mutation associated with autosomal recessive juvenile cataract in a Saudi family

1 reference

12 December 2020

Rosenthal fibers contain ubiquitinated alpha B-crystallin

1 reference

12 December 2020

The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines.

1 reference

12 December 2020

Crystallin gene mutations in Indian families with inherited pediatric cataract

1 reference

12 December 2020

Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II

1 reference

12 December 2020

Nuclear import of {alpha}B-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G

1 reference

12 December 2020

Identification of a novel, putative cataract-causing allele in CRYAA (G98R) in an Indian family

1 reference

12 December 2020

Identification by 1H NMR spectroscopy of flexible C-terminal extensions in bovine lens alpha-crystallin

1 reference

12 December 2020

Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2

1 reference

12 December 2020

Consequences of the molecular mechanism of amyloid formation for the understanding of the pathogenesis of Alzheimer's disease and the development of therapeutic strategies.

1 reference

12 December 2020

A novel HSPB1 mutation in an Italian patient with CMT2/dHMN phenotype

1 reference

12 December 2020

Structure and Function of the Conserved Domain in αA-Crystallin. Site-Directed Spin Labeling Identifies a β-Strand Located near a Subunit Interface

1 reference

12 December 2020

Crystallins, genes and cataract

1 reference

12 December 2020

C-terminal interactions mediate the quaternary dynamics of αB-crystallin.

1 reference

12 December 2020

Laser Raman spectroscopic studies of ocular lens and its isolated protein fractions

1 reference

12 December 2020

ODF1 phosphorylation by Cdk5/p35 enhances ODF1-OIP1 interaction

1 reference

12 December 2020

Characterization and purification of the small 28,000-dalton mammalian heat shock protein

1 reference

12 December 2020

A spectroscopic study of glycated bovine alpha-crystallin: investigation of flexibility of the C-terminal extension, chaperone activity and evidence for diglycation

1 reference

12 December 2020

10.1007/S00018-014-1754-5

Identifiers

DOI

1 reference

1 September 2017

1 reference