Chromatin remodeler mutations in human cancers: epigenetic implications (Q38261746)

1 September 2017

1 reference

title

Chromatin remodeler mutations in human cancers: epigenetic implications (English)

1 reference

1 September 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Phillippa C Taberlay

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Katherine A Skulte

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Lisa Phan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

1 January 2014

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1 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

397-414

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333849%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

cites work

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The epigenomics of cancer

21 January 2018

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Interplay between the cancer genome and epigenome

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Cancer genetics and epigenetics: two sides of the same coin?

21 January 2018

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The SWI/SNF complex and cancer

21 January 2018

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On the role of of histones in regulation ribonucleic acid synthesis in the cell nucleus

21 January 2018

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Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization

21 January 2018

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Histone modifications at human enhancers reflect global cell-type-specific gene expression

21 January 2018

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

21 January 2018

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Transcriptional and epigenetic dynamics during specification of human embryonic stem cells

21 January 2018

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The ISWI ATPase Snf2h is required for early mouse development

21 January 2018

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The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling

21 January 2018

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The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis

21 January 2018

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INO80-dependent regression of ecdysone-induced transcriptional responses regulates developmental timing in Drosophila

21 January 2018

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Chromatin modifiers and remodellers: regulators of cellular differentiation

21 January 2018

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Rapid and pervasive changes in genome-wide enhancer usage during mammalian development

21 January 2018

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The biology of chromatin remodeling complexes

21 January 2018

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SWI/SNF nucleosome remodellers and cancer.

21 January 2018

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Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling

21 January 2018

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A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex

21 January 2018

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Functional analysis of the subunits of the chromatin assembly factor RSF

21 January 2018

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ATP-dependent chromatin-remodeling complexes.

21 January 2018

1 reference

Nucleosome remodeling and epigenetics.

21 January 2018

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Mechanisms for nucleosome mobilization

21 January 2018

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The structure of DNA in the nucleosome core

21 January 2018

1 reference

Nucleosome remodeling: one mechanism, many phenomena?

21 January 2018

1 reference

Direct observation of DNA distortion by the RSC complex

21 January 2018

1 reference

Chromatin remodeling by DNA bending, not twisting

21 January 2018

1 reference

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

21 January 2018

1 reference

Spatial contacts and nucleosome step movements induced by the NURF chromatin remodeling complex

21 January 2018

1 reference

Dynamics of nucleosome remodelling by individual ACF complexes

21 January 2018

1 reference

ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps

21 January 2018

1 reference

Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities

21 January 2018

1 reference

SWI/SNF has intrinsic nucleosome disassembly activity that is dependent on adjacent nucleosomes

21 January 2018

1 reference

Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2

21 January 2018

1 reference

Chromatin remodeling during glucocorticoid receptor regulated transactivation.

21 January 2018

1 reference

An essential switch in subunit composition of a chromatin remodeling complex during neural development

21 January 2018

1 reference

Baf60c is essential for function of BAF chromatin remodelling complexes in heart development

21 January 2018

1 reference

Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions.

21 January 2018

1 reference

Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.

21 January 2018

1 reference

Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner

21 January 2018

1 reference

Cancer biology and NuRD: a multifaceted chromatin remodelling complex

21 January 2018

1 reference

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

21 January 2018

1 reference

An essential role for a mammalian SWI/SNF chromatin-remodeling complex during male meiosis

21 January 2018

1 reference

Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression.

21 January 2018

1 reference

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF

21 January 2018

1 reference

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

21 January 2018

1 reference

SNF2β-BRG1 is Essential for the Viability of F9 Murine Embryonal Carcinoma Cells

21 January 2018

1 reference

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development

21 January 2018

1 reference

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling

21 January 2018

1 reference

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

21 January 2018

1 reference

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle

21 January 2018

1 reference

21 January 2018

1 reference

Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression

21 January 2018

1 reference

Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control

21 January 2018

1 reference

BAF250B-associated SWI/SNF chromatin-remodeling complex is required to maintain undifferentiated mouse embryonic stem cells.

21 January 2018

1 reference

SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus

21 January 2018

1 reference

brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2

21 January 2018

1 reference

Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation

21 January 2018

1 reference

Chromatin modulation at the FLO11 promoter of Saccharomyces cerevisiae by HDAC and Swi/Snf complexes

21 January 2018

1 reference

Gcn5 regulates the dissociation of SWI/SNF from chromatin by acetylation of Swi2/Snf2.

21 January 2018

1 reference

SWI/SNF binding to the HO promoter requires histone acetylation and stimulates TATA-binding protein recruitment

21 January 2018

1 reference

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors.

21 January 2018

1 reference

Decreased ARID1A expression is correlated with chemoresistance in epithelial ovarian cancer

21 January 2018

1 reference

Gene silencing associated with SWI/SNF complex loss during NSCLC development.

21 January 2018

1 reference

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.

21 January 2018

1 reference

Reduced expression of the chromatin remodeling gene ARID1A enhances gastric cancer cell migration and invasion via downregulation of E-cadherin transcription

21 January 2018

1 reference

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

21 January 2018

1 reference

The spectrum of SWI/SNF mutations, ubiquitous in human cancers

21 January 2018

1 reference

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

21 January 2018

1 reference

Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer

21 January 2018

1 reference

Loss of ARID1A expression correlates with stages of tumor progression in uterine endometrioid carcinoma

21 January 2018

1 reference

Loss of ARID1A/BAF250a expression is linked to tumor progression and adverse prognosis in cervical cancer.

21 January 2018

1 reference

Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations, TP53 and microsatellite instability in endometrial cancer.

21 January 2018

1 reference

BRG1 is a prognostic marker and potential therapeutic target in human breast cancer

21 January 2018

1 reference

The role of SMARCB1/INI1 in development of rhabdoid tumor.

21 January 2018

1 reference

Driver mutations of cancer epigenomes.

21 January 2018

1 reference

The SWI/SNF complex--chromatin and cancer.

21 January 2018

1 reference

Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation

21 January 2018

1 reference

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers

21 January 2018

1 reference

Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability.

21 January 2018

1 reference

Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

21 January 2018

1 reference

Nucleosome dynamics define transcriptional enhancers

21 January 2018

1 reference

Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells

21 January 2018

1 reference

Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1

21 January 2018

1 reference

Brg1-dependent epigenetic control of vascular smooth muscle cell proliferation by hydrogen sulfide

21 January 2018

1 reference

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

21 January 2018

1 reference

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription

21 January 2018

1 reference

Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level

21 January 2018

1 reference

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

21 January 2018

1 reference

A role of the amino-terminal (N) and carboxyl-terminal (C) interaction in binding of androgen receptor to chromatin

21 January 2018

1 reference

Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex

21 January 2018

1 reference

Differential requirement of SWI/SNF for androgen receptor activity

21 January 2018

1 reference

Reprogramming of the SWI/SNF complex for co-activation or co-repression in prohibitin-mediated estrogen receptor regulation

21 January 2018

1 reference

BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

21 January 2018

1 reference

Molecular pathways in prostate cancer

21 January 2018

1 reference

Effect of estrogen receptor α binding on functional DNA methylation in breast cancer

21 January 2018

1 reference

Specific activity of class II histone deacetylases in human breast cancer cells

21 January 2018

1 reference

Targeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model

21 January 2018

1 reference

Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer

21 January 2018

1 reference

Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails

21 January 2018

1 reference

Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14

21 January 2018

1 reference

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.

21 January 2018

1 reference

Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.

21 January 2018

1 reference

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

21 January 2018

1 reference

Relationship between nucleosome positioning and DNA methylation

21 January 2018

1 reference

Identification of preferential target sites for human DNA methyltransferases

21 January 2018

1 reference

Effects of DNA methylation on nucleosome stability

21 January 2018

1 reference

Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.

21 January 2018

1 reference

Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules

21 January 2018

1 reference

Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance

21 January 2018

1 reference

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes

21 January 2018

1 reference

Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning

21 January 2018

1 reference

SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation

21 January 2018

1 reference

Contrasting chromatin organization of CpG islands and exons in the human genome

21 January 2018

1 reference

DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure

21 January 2018

1 reference

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

21 January 2018

1 reference

CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

21 January 2018

1 reference

The human SWI/SNF subunit Brm is a regulator of alternative splicing

21 January 2018

1 reference

The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit

21 January 2018

1 reference

The reversible epigenetic silencing of BRM: implications for clinical targeted therapy.

21 January 2018

1 reference

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a

21 January 2018

1 reference

SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development

21 January 2018

1 reference

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

1 reference