Pannexin channels and their links to human disease (Q38227797)

31 August 2017

title

Pannexin channels and their links to human disease (English)

1 reference

31 August 2017

Silvia Penuela

1

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Dale W Laird

object named as

Dale W Laird

series ordinal

4

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author name string

Luke Harland

series ordinal

2

1 reference

31 August 2017

Jamie Simek

series ordinal

3

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31 August 2017

language of work or name

English

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publication date

1 August 2014

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31 August 2017

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31 August 2017

volume

461

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31 August 2017

issue

3

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31 August 2017

page(s)

371-381

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Connexins, connexons, and intercellular communication

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Innexins form two types of channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Innexins: members of an evolutionarily conserved family of gap-junction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Connections with connexins: the molecular basis of direct intercellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

A ubiquitous family of putative gap junction molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Cell-cell communication beyond connexins: the pannexin channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin channels are not gap junction hemichannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Connexins, pannexins, innexins: novel roles of "hemi-channels"

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Gap junctional proteins of animals: the innexin/pannexin superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Glycosylation regulates pannexin intermixing and cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Patterns of heterogeneous expression of pannexin 1 and pannexin 2 transcripts in the olfactory epithelium and olfactory bulb

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Expression of pannexin family of proteins in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 and Pannexin2 expression in the developing and mature rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 3 functions as an ER Ca2+ channel, hemichannel, and gap junction to promote osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Evolution of gap junction proteins--the pannexin alternative.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

SCAM analysis of Panx1 suggests a peculiar pore structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

The biochemistry and function of pannexin channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexins, a family of gap junction proteins expressed in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin membrane channels are mechanosensitive conduits for ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

The pannexin 1 channel activates the inflammasome in neurons and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

P2X7 receptor-Pannexin1 complex: pharmacology and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Connexin and pannexin mediated cell-cell communication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Probenecid, a gout remedy, inhibits pannexin 1 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

The P2X7 receptor–pannexin-1 complex decreases muscarinic acetylcholine receptor–mediated seizure susceptibility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 1 in erythrocytes: function without a gap

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Panx1 regulates neural stem and progenitor cell behaviours associated with cytoskeletal dynamics and interacts with multiple cytoskeletal elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Powerful partnership: crosstalk between pannexin 1 and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Physiological mechanisms for the modulation of pannexin 1 channel activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Diverse post-translational modifications of the pannexin family of channel-forming proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Single Cysteines in the Extracellular and Transmembrane Regions Modulate Pannexin 1 Channel Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Intracellular Cysteine 346 Is Essentially Involved in Regulating Panx1 Channel Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

S-nitrosylation inhibits pannexin 1 channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Anoxia-induced NMDA receptor activation opens pannexin channels via Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Regulation of pannexin channels by post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Tumor-suppressive effects of pannexin 1 in C6 glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 drives multicellular aggregate compaction via a signaling cascade that remodels the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin2 as a novel growth regulator in C6 glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 and Pannexin3 exhibit distinct localization patterns in human skin appendages and are regulated during keratinocyte differentiation and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Ischemia opens neuronal gap junction hemichannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Probenecid protects against transient focal cerebral ischemic injury by inhibiting HMGB1 release and attenuating AQP4 expression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexins in ischemia-induced neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Functional outcome of pannexin-deficient mice after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Targeting pannexin1 improves seizure outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Elevated pressure triggers a physiological release of ATP from the retina: Possible role for pannexin hemichannels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Expression and localization of pannexin-1 hemichannels in human colon in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Connexin and pannexin hemichannels in inflammatory responses of glia and neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Contribution of pannexin1 to experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

ATP released via pannexin-1 hemichannels mediates bladder overactivity triggered by urothelial P2Y6 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Differentiating connexin hemichannels and pannexin channels in cellular ATP release

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Panx1 regulates cellular properties of keratinocytes and dermal fibroblasts in skin development and wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Spreading depression triggers headache by activating neuronal Panx1 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Expression of pannexin isoforms in the systemic murine arterial network

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Haemolysis induced by α-toxin from Staphylococcus aureus requires P2X receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Editorial: Pannexin-1--the hidden gatekeeper for HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Genome-wide analyses of gene expression during mouse endochondral ossification

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

What is hidden in the pannexin treasure trove: the sneak peek and the guesswork

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Diverse subcellular distribution profiles of pannexin 1 and pannexin 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Functional implications of calcium permeability of the channel formed by pannexin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Regulation of cellular communication by signaling microdomains in the blood vessel wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Unexpected link between an antibiotic, pannexin channels and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Trafficking dynamics of glycosylated pannexin 1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140447

21 January 2018

Identifiers

DOI

10.1042/BJ20140447

1 reference

31 August 2017

1 reference