Human DNA ligases: a comprehensive new look for cancer therapy (Q38130159)

29 August 2017

title

Human DNA ligases: a comprehensive new look for cancer therapy (English)

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29 August 2017

author name string

Deependra Kumar Singh

1

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29 August 2017

Shagun Krishna

2

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29 August 2017

Sharat Chandra

3

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29 August 2017

Mohammad Shameem

4

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29 August 2017

Amit Laxmikant Deshmukh

5

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29 August 2017

Dibyendu Banerjee

6

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29 August 2017

publication date

19 August 2013

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Medicinal Research Reviews

29 August 2017

published in

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29 August 2017

volume

34

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29 August 2017

issue

3

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29 August 2017

page(s)

567-595

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DNA ligase: structure, mechanism, and function

29 August 2017

cites work

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DNA and RNA ligases: structural variations and shared mechanisms

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21 January 2018

Bacterial DNA ligases.

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Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner

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DNA repair in mammalian cells: Base excision repair: the long and short of it.

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Yeast DNA ligase IV mediates non-homologous DNA end joining

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Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

21 January 2018

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Eukaryotic DNA ligases: structural and functional insights

21 January 2018

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Nijmegen breakage syndrome (NBS)

21 January 2018

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Structure of the human DNA ligase I gene

21 January 2018

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Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta

21 January 2018

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Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents

21 January 2018

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Growth retardation and immunodeficiency in a patient with mutations in the DNA ligase I gene

21 January 2018

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Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I

21 January 2018

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Mammalian DNA nucleotide excision repair reconstituted with purified protein components.

21 January 2018

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The human DNA ligase III gene encodes nuclear and mitochondrial proteins

21 January 2018

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Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair.

21 January 2018

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DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

21 January 2018

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Impact of DNA ligase IV on the fidelity of end joining in human cells

21 January 2018

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Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

21 January 2018

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Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway

21 January 2018

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Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells

21 January 2018

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Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells

21 January 2018

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MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

21 January 2018

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DNA ligases in the repair and replication of DNA.

21 January 2018

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DNA double-strand break repair

21 January 2018

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Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination

21 January 2018

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DNA ligase IV from HeLa cell nuclei

21 January 2018

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Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

21 January 2018

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Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

21 January 2018

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Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

21 January 2018

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Targeting abnormal DNA repair in therapy-resistant breast cancers

21 January 2018

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Human DNA ligase I completely encircles and partially unwinds nicked DNA

21 January 2018

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Identification and validation of human DNA ligase inhibitors using computer-aided drug design

21 January 2018

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Location of the active site for enzyme-adenylate formation in DNA ligases

21 January 2018

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Inhibition of human DNA ligase I activity by zinc and cadmium and the fidelity of ligation.

21 January 2018

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Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair

21 January 2018

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Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining

21 January 2018

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An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression

21 January 2018

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Structural Insights into the Role of Domain Flexibility in Human DNA Ligase IV

21 January 2018

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Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and biological review

21 January 2018

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Correlation between anthracycline structure and human DNA ligase inhibition

21 January 2018

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Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity

21 January 2018

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Historical perspectives on cadmium toxicology

21 January 2018

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Inhibition of RNA-directed DNA polymerase by aurintricarboxylic acid

21 January 2018

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Development of non-electrophoretic assay method for DNA ligases and its application to screening of chemical inhibitors of DNA ligase I.

21 January 2018

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Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

21 January 2018

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NAD(+)-dependent DNA ligase: a novel target waiting for the right inhibitor.

21 January 2018

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Natural-product inhibitors of human DNA ligase I.

21 January 2018

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DNA ligase I gene expression during differentiation and cell proliferation

21 January 2018

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PARP inhibitors stumble in breast cancer

21 January 2018

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Therapeutic applications of PARP inhibitors: anticancer therapy and beyond

21 January 2018

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Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias

21 January 2018

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

21 January 2018

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DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories

21 January 2018

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Identification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA Replication

21 January 2018

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Phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair

21 January 2018

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Cell cycle-dependent phosphorylation of human DNA ligase I at the cyclin-dependent kinase sites.

21 January 2018

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Accelerating cancer therapy development: the importance of combination strategies and collaboration. Summary of an Institute of Medicine workshop

21 January 2018

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Structure and Synthesis of Distamycin A

21 January 2018

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Fagaronine, a new tumor inhibitor isolated from Fagara zanthoxyloides Lam. (Rutaceae)

21 January 2018

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COCI

https://opencitations.net/index/api/v1/citations/10.1002/JPS.2600611145

23 March 2024

Identifiers

DOI

10.1002/MED.21298

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29 August 2017

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